C12NMICROORGANISMS OR ENZYMESCOMPOSITIONS THEREOFPROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMSMUTATION OR GENETIC ENGINEERINGCULTURE MEDIA microbiological testing media C12Q1/00Attention is drawn to Notes (1) to (3) following the title of class C12.Biocidal, pest repellant, pest attractant or plant growth regulatory activity of compounds or preparations is further classified in subclass A01P.Therapeutic activity of single-cell proteins or enzymes is further classified in subclass A61P.When classifying in this subclass, classification is also made in group B01D15/08 insofar as subject matter of general interest relating to chromatography is concerned.In this subclass, it is desirable to add the indexing codes of subclass C12R.Documents relating to the use of vectors or hosts for the preparation of specific peptides, e.g. enzymes, are classified in subclass C07K or in group C12N9/00 according to the peptides, with the appropriate indexing codes.In this subclass, combination sets [C-Sets] are used. The detailed information about the C-Sets construction and the associated syntax rules is present in the definitions of C12N.The following IPC groups are not in the CPC scheme. The subject matter for these IPC groups is classified in the following CPC groups: C12N1/11 covered by C12N15/79C12N1/13 covered by C12N15/79C12N1/15 covered by C12N15/80C12N1/19 covered by C12N15/81C12N1/21 covered by C12N15/74C12N5/02 covered by C12N5/0006, C12N5/04 - C12N5/166C12N5/07 - C12N5/095 covered by C12N5/06 C12N5/18 covered by C12N5/16C12N5/20 covered by C12N5/163C12N5/22 covered by C12N5/16C12N5/24 covered by C12N5/163C12N5/26 covered by C12N5/166C12N5/28 covered by C12N5/166C12N15/53 covered by C12N9/0004C12N7/01 covered by C12N7/00C12N9/02-C12N9/08 covered by C12N9/0004C12N9/26 covered by C12N9/2408C12N9/28-C12N9/30 covered by C12N9/2414 - C12N9/242 C12N9/32 covered by C12N9/2422 C12N9/34 covered by C12N9/2428 C12N9/36 covered by C12N9/2462 C12N9/38 covered by C12N9/2468C12N9/40 covered by C12N9/2465 C12N9/42 covered by C12N9/2434C12N9/44 covered by C12N9/2451C12N9/46 covered by C12N9/2454 C12N9/56 covered by C12N9/54 C12N9/66 covered by C12N9/6448 C12N9/68 covered by C12N9/6435 C12N9/70 covered by C07K14/3153C12N9/72 covered by C12N9/6462 C12N9/74 covered by C12N9/6429 C12N9/76 covered by C12N9/6427 C12N15/05 covered by C12N5/14C12N15/06 covered by C12N5/16C12N15/07 covered by C12N5/16C12N15/08 covered by C12N5/166C12N15/12 covered by C07K14/435C12N15/13 covered by C07K16/00C12N15/14 covered by C07K14/765C12N15/15 covered by C07K14/81C12N15/16 covered by C07K14/575C12N15/17 covered by C07K14/62C12N15/18 covered by C07K14/61C12N15/19 covered by C07K14/52C12N15/20 covered by C07K14/555C12N15/21 covered by C07K14/56C12N15/22 covered by C07K14/565C12N15/23 covered by C07K14/57C12N15/24 covered by C07K14/54C12N15/25 covered by C07K14/545C12N15/26 covered by C07K14/55C12N15/27 covered by C07K14/53C12N15/28 covered by C07K14/525C12N15/29 covered by C07K14/415C12N15/30 covered by C07K14/44C12N15/31 covered by C07K14/195, C07K14/005C12N15/32 covered by C07K14/325C12N15/33 covered by C07K14/005C12N15/34 covered by C07K14/01C12N15/35 covered by C07K14/015C12N15/36 covered by C07K14/02C12N15/37 covered by C07K14/025C12N15/38 covered by C07K14/03C12N15/39 covered by C07K14/065C12N15/40 covered by C07K14/08C12N15/41 covered by C07K14/085C12N15/42 covered by C07K14/09C12N15/43 covered by C07K14/105C12N15/44 covered by C07K14/11C12N15/45 covered by C07K14/115C12N15/46 covered by C07K14/14C12N15/47 covered by C07K14/145C12N15/48 covered by C07K14/15C12N15/49 covered by C07K14/155C12N15/50 covered by C07K14/165C12N15/51 covered by C07K14/02, C07K14/10, C07K14/18C12N15/53 covered by C12N9/0004C12N15/54 covered by C12N9/10C12N15/55 covered by C12N9/14C12N15/56 covered by C12N9/24C12N15/57 covered by C12N9/48C12N15/58 covered by C12N9/6456C12N15/59 covered by C12N9/6483C12N15/60 covered by C12N9/88C12N15/61 covered by C12N9/90C12N15/83 covered by C12N15/82C12N15/84 covered by C12N15/82
In this subclass non-limiting references (in the sense of paragraph 39 of the Guide to the IPC) may still be displayed in the scheme.
C12N1/00 C12N1/00Microorganisms, e.g. protozoaCompositions thereof medicinal preparations containing material from protozoa, bacteria or viruses A61K35/66, from algae A61K36/02, from fungi A61K36/06; preparing medicinal bacterial antigen or antibody compositions, e.g. bacterial vaccines, A61K39/00Processes of propagating, maintaining or preserving microorganisms or compositions thereofProcesses of preparing or isolating a composition containing a microorganismCulture media therefor C12N1/005after treatment of microbial biomass not covered by C12N1/02 - C12N1/08 C12N1/02Separating microorganisms from their culture media C12N1/04Preserving or maintaining viable microorganisms immobilised microorganisms C12N11/00 C12N1/06Lysis of microorganisms C12N1/063of yeast C12N1/066by physical methods C12N1/08Reducing the nucleic acid content C12N1/10ProtozoaCulture media therefor C12N1/105Protozoal isolates C12N1/12Unicellular algaeCulture media therefor as new plants A01H13/00 C12N1/125Unicellular algae isolates C12N1/14Fungi culture of mushrooms A01G18/00; as new plants A01H15/00Culture media therefor C12N1/145Fungal isolates C12N1/16YeastsCulture media therefor C12N1/165Yeast isolates C12N1/18Baker's yeastBrewer's yeast C12N1/185Saccharomyces isolates C12N1/20BacteriaCulture media therefor C12N1/205Bacterial isolates C12N1/22Processes using, or culture media containing, cellulose or hydrolysates thereof C12N1/24Processes using, or culture media containing, waste sulfite liquor C12N1/26Processes using, or culture media containing, hydrocarbons refining of hydrocarbon oils by using microorganisms C10G32/00 C12N1/28aliphatic C12N1/30having five or less carbon atoms C12N1/32Processes using, or culture media containing, lower alkanols, i.e. C1 to C6 C12N1/34Processes using foam culture C12N1/36Adaptation or attenuation of cells C12N1/38Chemical stimulation of growth or activity by addition of chemical compounds which are not essential growth factorsStimulation of growth by removal of a chemical compound C12N1/34 takes precedence C12N3/00Spore forming or isolating processes C12N5/00Undifferentiated human, animal or plant cells, e.g. cell linesTissuesCultivation or maintenance thereofCulture media therefor; plant reproduction by tissue culture techniques A01H4/00In this group, the following words are used with the meanings indicated: a "totipotent" cell can differentiate into all somatic lineages (ectoderm, mesoderm, endoderm), the germ line and extra-embryonic tissues such as the placenta; a "pluripotent" cell is a somatic stem cell which can differentiate into cells of at least two of the three somatic lineages (ectoderm, mesoderm, endoderm); a "multipotent" cell is restricted to one lineage; "progenitor" and "precursor" cells are further restricted within the lineage. If not explicitly forseen, totipotent cells are classified with pluripotent cells. Multipotent cells should not be classified with pluripotent cells. Unless provided for otherwise, committed progenitors are classified with their progeny. C12N5/0006Modification of the membrane of cells, e.g. cell decoration C12N5/0012Cell encapsulation C12N5/0018Culture media for cell or tissue culture media for specific animal cell type C12N5/06 C12N5/0025Culture media for plant cell or plant tissue culture C12N5/0031Serum-free culture media This group is no longer used for the classification of new documents as from 2012-01-01. The backlog of this group is being continuously reclassified to C12N5/0037 - C12N5/0056 C12N5/0037Serum-free medium, which may still contain naturally-sourced components C12N5/0043Medium free of human- or animal-derived components C12N5/005Protein-free medium C12N5/0056Xeno-free medium C12N5/0062General methods for three-dimensional culture C12N5/0068General culture methods using substrates for specific animal cell type C12N5/06 C12N5/0075using microcarriers C12N5/0081Purging biological preparations of unwanted cells C12N5/0087Purging against subsets of blood cells, e.g. purging alloreactive T cells C12N5/0093Purging against cancer cells C12N5/04Plant cells or tissues culture media C12N5/0025 C12N5/06Animal cells or tissues; Human cells or tissues preservation of living cells or tissues A01N1/02 In this group, the following words are used with the meanings indicated: a "totipotent" cell can differentiate into all somatic lineages (ectoderm, mesoderm, endoderm), the germ line and extra-embryonic tissues such as the placenta; a "pluripotent" cell is a somatic stem cell which can differentiate into cells of at least two of the three somatic lineages (ectoderm, mesoderm, endoderm); a "multipotent" cell is restricted to one lineage. "Progenitor" and "precursor" cells are further restricted within the lineage. If not explicitly forseen, totipotent cells are classified with pluripotent cells. Multipotent cells should not be classified with pluripotent cells. The last place priority rule does not apply between the subgroups of this group C12N5/0601Invertebrate cells or tissues, e.g. insect cells; Culture media therefor C12N5/0602Vertebrate cellsThree-dimensional culture, tissue culture or organ culture are classified with the corresponding cells, if not specially provided for C12N5/0603Embryonic cells production of embryos, nuclear transfer A01K67/027; Embryoid bodies C12N5/0604Whole embryos; Culture medium therefor C12N5/0605Cells from extra-embryonic tissues, e.g. placenta, amnion, yolk sac, Wharton's jelly C12N5/0606Pluripotent embryonic cells, e.g. embryonic stem cells [ES] embryonic germ cells C12N5/0611, induced pluripotent stem cells C12N5/0696 C12N5/0607Non-embryonic pluripotent stem cells, e.g. MASC induced pluripotent stem cells C12N5/0696 C12N5/0608Germ cells production of embryos, nuclear transfer A01K67/027 C12N5/0609Oocytes, oogonia fertilised oocytes C12N5/0604 C12N5/061Sperm cells, spermatogonia C12N5/0611Primordial germ cells, e.g. embryonic germ cells [EG] C12N5/0612sorting of gametes, e.g. according to sex or motility C12N5/0613Cells from endocrine organs pancreas C12N5/0676, gonads C12N5/0681 C12N5/0614Adrenal gland C12N5/0615Pineal gland C12N5/0616Pituitary gland C12N5/0617Thyroid and parathyroid glands C12N5/0618Cells of the nervous system C12N5/0619Neurons C12N5/062Sensory transducers, e.g. photoreceptors; Sensory neurons, e.g. for hearing, taste, smell, pH, touch, temperature, pain C12N5/0621Eye cells, e.g. cornea, iris pigmented cells photoreceptors C12N5/062 C12N5/0622Glial cells, e.g. astrocytes, oligodendrocytes; Schwann cells C12N5/0623Stem cells C12N5/0625Epidermal cells, skin cells; Cells of the oral mucosa C12N5/0626Melanocytes C12N5/0627Hair cells C12N5/0628Hair stem cells; Hair progenitors mesenchymal stem cells from hair follicles C12N5/0666 C12N5/0629Keratinocytes; Whole skin C12N5/063Kereatinocyte stem cells; Keratinocyte progenitors C12N5/0631Mammary cells C12N5/0632Cells of the oral mucosa C12N5/0633Cells of secretory glands, e.g. parotid gland, salivary glands, sweat glands, lacrymal glands C12N5/0634Cells from the blood or the immune systemCommitted progenitors are classified with their progeny C12N5/0635B lymphocytes C12N5/0636T lymphocytes C12N5/0637Immunosuppressive T lymphocytes, e.g. regulatory T cells (Treg) C12N5/0638Cytotoxic T lymphocytes [CTL], lymphokine activated killer cells [LAK] C12N5/0639Dendritic cells, e.g. Langherhans cells in the epidermis C12N5/064Immunosuppressive dendritic cells C12N5/0641Erythrocytes C12N5/0642Granulocytes, e.g. basopils, eosinophils, neutrophils, mast cells C12N5/0643Osteoclasts C12N5/0644Platelets; Megakaryocytes C12N5/0645Macrophages, e.g. Kuepfer cells in the liver; Monocytes C12N5/0646Natural killers cells [NK], NKT cells C12N5/0647Haematopoietic stem cells; Uncommitted or multipotent progenitors C12N5/0648Splenocytes C12N5/065Thymocytes C12N5/0651Lymph nodes C12N5/0652Cells of skeletal and connective tissues; Mesenchyme C12N5/0653Adipocytes; Adipose tissue C12N5/0654Osteocytes, Osteoblasts, Odontocytes; Bones, Teeth C12N5/0655Chondrocytes; Cartilage C12N5/0656Adult fibroblasts C12N5/0657Cardiomyocytes; Heart cells C12N5/0658Skeletal muscle cells, e.g. myocytes, myotubes, myoblasts C12N5/0659Satellite cells C12N5/066Tenocytes; Tendons, Ligaments C12N5/0661Smooth muscle cells C12N5/0662Stem cells C12N5/0663Bone marrow mesenchymal stem cells (BM-MSC) C12N5/0664Dental pulp stem cells, Dental follicle stem cells C12N5/0665Blood-borne mesenchymal stem cells, e.g. from umbilical cord blood C12N5/0666Mesenchymal stem cells from hair follicles C12N5/0667Adipose-derived stem cells [ADSC]; Adipose stromal stem cells C12N5/0668Mesenchymal stem cells from other natural sources C12N5/0669Bone marrow stromal cells; Whole bone marrow isolated stem cells from bone marrow C12N5/0647, C12N5/0663 C12N5/067Hepatocytes C12N5/0671Three-dimensional culture, tissue culture or organ culture; Encapsulated cells C12N5/0672Stem cells; Progenitor cells; Precursor cells; Oval cells C12N5/0676Pancreatic cells C12N5/0677Three-dimensional culture, tissue culture or organ culture; Encapsulated cells C12N5/0678Stem cells; Progenitor cells; Precursor cells C12N5/0679Cells of the gastro-intestinal tract C12N5/068Stem cells; Progenitors C12N5/0681Cells of the genital tract; Non-germinal cells from gonads C12N5/0682Cells of the female genital tract, e.g. endometrium; Non-germinal cells from ovaries, e.g. ovarian follicle cells oocytes C12N5/0609 C12N5/0683Cells of the male genital tract, e.g. prostate, epididymis; Non-germinal cells from testis, e.g. Leydig cells, Sertoli cells spermatogonia C12N5/061 C12N5/0684Cells of the urinary tract or kidneys C12N5/0685Bladder epithelial cells C12N5/0686Kidney cells C12N5/0687Renal stem cells; Renal progenitors C12N5/0688Cells from the lungs or the respiratory tract C12N5/0689Stem cells; Progenitors C12N5/069Vascular Endothelial cells C12N5/0691Vascular smooth muscle cells; 3D culture thereof, e.g. models of blood vessels C12N5/0692Stem cells; Progenitor cells; Precursor cells C12N5/0693Tumour cells; Cancer cells C12N5/0694Cells of blood, e.g. leukemia cells, myeloma cells C12N5/0695Stem cells; Progenitor cells; Precursor cells C12N5/0696Artificially induced pluripotent stem cells, e.g. iPS C12N5/0697Artificial constructs associating cells of different lineages, e.g. tissue equivalents blood vessels C12N5/0691 C12N5/0698Skin equivalents C12N5/10Cells modified by introduction of foreign genetic material C12N5/12Fused cells, e.g. hybridomas C12N5/14Plant cells C12N5/16Animal cells C12N5/163one of the fusion partners being a B or a T lymphocyte C12N5/166resulting from interspecies fusion C12N7/00VirusesBacteriophagesCompositions thereofPreparation or purification thereof preparing medicinal viral antigen or antibody compositions, e.g. virus vaccines, A61K39/00 From 2012-03-15 groups C12N7/02 - C12N7/08 and subgroups thereof are no longer used for the classification of new documents. The documents in these (sub)groups are being reclassified to the corresponding codes in the range C12N2710/00-C12N2795/00. C12N7/02Recovery or purification C12N7/025Packaging cell lines, e.g. transcomplementing cell lines, for production of virus C12N7/04Inactivation or attenuationProducing viral sub-units C12N7/045Pseudoviral particles; Non infectious pseudovirions, e.g. genetically engineered C12N7/06Inactivation or attenuation by chemical treatment C12N7/08Inactivation or attenuation by serial passage of virus C12N9/00EnzymesProenzymesCompositions thereof preparations containing enzymes for cleaning teeth A61K8/66, A61Q11/00; medicinal preparations containing enzymes or proenzymes A61K38/43; enzyme containing detergent compositions C11D; enzymes with nucleic acid structure, e.g. ribozymes, C12N15/113Processes for preparing, activating, inhibiting, separating or purifying enzymes preparation of malt C12C1/00Enzymes are generally categorized below according to the "Nomenclature and Classification of Enzymes" of the International Commission on Enzymes. Where appropriate, this designation appears in the groups below in parenthesis. C12N9/0002Antibodies with enzymatic activity, e.g. abzymes C12N9/0004Oxidoreductases (1.) C12N9/0006acting on CH-OH groups as donors (1.1) C12N9/0008acting on the aldehyde or oxo group of donors (1.2) C12N9/001acting on the CH-CH group of donors (1.3) C12N9/0012acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) C12N9/0014acting on the CH-NH2 group of donors (1.4) C12N9/0016with NAD or NADP as acceptor (1.4.1) C12N9/0018Phenylalanine dehydrogenase (1.4.1.20) C12N9/002with a cytochrome as acceptor (1.4.2) C12N9/0022with oxygen as acceptor (1.4.3) C12N9/0024D-Amino acid oxidase (1.4.3.3) C12N9/0026acting on CH-NH groups of donors (1.5) C12N9/0028with NAD or NADP as acceptor (1.5.1) C12N9/003Dihydrofolate reductase [DHFR] (1.5.1.3) C12N9/0032with oxygen as acceptor (1.5.3) C12N9/0034Sarcosine oxidase (1.5.3.1) C12N9/0036acting on NADH or NADPH (1.6) C12N9/0038with a heme protein as acceptor (1.6.2) C12N9/004Cytochrome-b5 reductase (1.6.2.2) C12N9/0042NADPH-cytochrome P450 reductase (1.6.2.4) C12N9/0044acting on other nitrogen compounds as donors (1.7) C12N9/0046with oxygen as acceptor (1.7.3) C12N9/0048Uricase (1.7.3.3) C12N9/0051acting on a sulfur group of donors (1.8) C12N9/0053acting on a heme group of donors (1.9) C12N9/0055acting on diphenols and related substances as donors (1.10) C12N9/0057with oxygen as acceptor (1.10.3) C12N9/0059Catechol oxidase (1.10.3.1), i.e. tyrosinase C12N9/0061Laccase (1.10.3.2) C12N9/0063Ascorbate oxidase (1.10.3.3) C12N9/0065acting on hydrogen peroxide as acceptor (1.11) C12N9/0067acting on hydrogen as donor (1.12) C12N9/0069acting on single donors with incorporation of molecular oxygen, i.e. oxygenases (1.13) C12N9/0071acting on paired donors with incorporation of molecular oxygen (1.14) C12N9/0073with NADH or NADPH as one donor, and incorporation of one atom of oxygen 1.14.13 C12N9/0075Nitric-oxide synthase (1.14.13.39) C12N9/0077with a reduced iron-sulfur protein as one donor (1.14.15) C12N9/0079Steroid 11 beta monooxygenase (P-450 protein)(1.14.15.4) C12N9/0081Cholesterol monooxygenase (cytochrome P 450scc)(1.14.15.6) C12N9/0083Miscellaneous (1.14.99) C12N9/0085Steroid 17 alpha-monooxygenase (1.14.99.9) C12N9/0087Steroid 21-monooxygenase (1.14.99.10) C12N9/0089acting on superoxide as acceptor (1.15) C12N9/0091oxidizing metal ions (1.16) C12N9/0093acting on CH or CH2 groups (1.17) C12N9/0095acting on iron-sulfur proteins as donor (1.18) C12N9/0097acting on reduced flavodoxin as donor (1.19) C12N9/10Transferases (2.) ribonucleases C12N9/22 C12N9/1003transferring one-carbon groups (2.1) C12N9/1007Methyltransferases (general) (2.1.1.) C12N9/1011Catechol O-methyltransferase (2.1.1.6) C12N9/1014Hydroxymethyl-, formyl-transferases (2.1.2) C12N9/1018Carboxy- and carbamoyl transferases (2.1.3) C12N9/1022transferring aldehyde or ketonic groups (2.2) C12N9/1025Acyltransferases (2.3) C12N9/1029transferring groups other than amino-acyl groups (2.3.1) C12N9/1033Chloramphenicol O-acetyltransferase (2.3.1.28) C12N9/1037Naringenin-chalcone synthase (2.3.1.74), i.e. chalcone synthase C12N9/104Aminoacyltransferases (2.3.2) C12N9/1044Protein-glutamine gamma-glutamyltransferase (2.3.2.13), i.e. transglutaminase or factor XIII C12N9/1048Glycosyltransferases (2.4) C12N9/1051Hexosyltransferases (2.4.1) C12N9/1055Levansucrase (2.4.1.10) C12N9/1059Cellulose synthases (2.4.1.12; 2.4.1.29) C12N9/1062Sucrose synthase (2.4.1.13) C12N9/1066Sucrose phosphate synthase (2.4.1.14) C12N9/1071,4-Alpha-glucan branching enzyme (2.4.1.18) C12N9/1074Cyclomaltodextrin glucanotransferase (2.4.1.19) C12N9/1077Pentosyltransferases (2.4.2) C12N9/1081transferring other glycosyl groups (2.4.99) C12N9/1085transferring alkyl or aryl groups other than methyl groups (2.5) C12N9/1088Glutathione transferase (2.5.1.18) C12N9/10923-Phosphoshikimate 1-carboxyvinyltransferase (2.5.1.19), i.e. 5-enolpyruvylshikimate-3-phosphate synthase C12N9/1096transferring nitrogenous groups (2.6) C12N9/12transferring phosphorus containing groups, e.g. kinases (2.7) C12N9/1205Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases C12N9/1211Thymidine kinase (2.7.1.21) C12N9/1217Phosphotransferases with a carboxyl group as acceptor (2.7.2) C12N9/1223Phosphotransferases with a nitrogenous group as acceptor (2.7.3) C12N9/1229Phosphotransferases with a phosphate group as acceptor (2.7.4) C12N9/1235Diphosphotransferases (2.7.6) C12N9/1241Nucleotidyltransferases (2.7.7) C12N9/1247DNA-directed RNA polymerase (2.7.7.6) C12N9/1252DNA-directed DNA polymerase (2.7.7.7), i.e. DNA replicase C12N9/1258Polyribonucleotide nucleotidyltransferase (2.7.7.8), i.e. polynucleotide phosphorylase C12N9/1264DNA nucleotidylexotransferase (2.7.7.31), i.e. terminal nucleotidyl transferase C12N9/127RNA-directed RNA polymerase (2.7.7.48), i.e. RNA replicase C12N9/1276RNA-directed DNA polymerase (2.7.7.49), i.e. reverse transcriptase or telomerase C12N9/1282RNA uridylyltransferase (2.7.7.52) C12N9/1288Transferases for other substituted phosphate groups (2.7.8) C12N9/1294Phosphotransferases with paired acceptors (2.7.9) C12N9/13transferring sulfur containing groups (2.8) C12N9/14Hydrolases (3) C12N9/16acting on ester bonds (3.1) C12N9/18Carboxylic ester hydrolases (3.1.1) C12N9/20Triglyceride splitting, e.g. by means of lipase C12N9/22Ribonucleases RNAses, DNAses catalytic nucleic acids C12N15/113 C12N9/24acting on glycosyl compounds (3.2) C12N9/2402hydrolysing O- and S- glycosyl compounds (3.2.1) C12N9/2405Glucanases C12N9/2408acting on alpha -1,4-glucosidic bonds C12N9/2411Amylases C12N9/2414Alpha-amylase (3.2.1.1.) C12N9/2417from microbiological source C12N9/242Fungal source C12N9/2422from plant source C12N9/2425Beta-amylase (3.2.1.2) C12N9/2428Glucan 1,4-alpha-glucosidase (3.2.1.3), i.e. glucoamylase C12N9/2431Beta-fructofuranosidase (3.2.1.26), i.e. invertase C12N9/2434acting on beta-1,4-glucosidic bonds C12N9/2437Cellulases (3.2.1.4; 3.2.1.74; 3.2.1.91; 3.2.1.150) C12N9/244Endo-1,3(4)-beta-glucanase (3.2.1.6) C12N9/2442Chitinase (3.2.1.14) C12N9/2445Beta-glucosidase (3.2.1.21) C12N9/2448Licheninase (3.2.1.73) C12N9/2451acting on alpha-1,6-glucosidic bonds C12N9/2454Dextranase (3.2.1.11) C12N9/2457Pullulanase (3.2.1.41) C12N9/246Isoamylase (3.2.1.68) C12N9/2462Lysozyme (3.2.1.17) C12N9/2465acting on alpha-galactose-glycoside bonds, e.g. alpha-galactosidase (3.2.1.22) C12N9/2468acting on beta-galactose-glycoside bonds, e.g. carrageenases (3.2.1.83; 3.2.1.157); beta-agarase (3.2.1.81) C12N9/2471Beta-galactosidase (3.2.1.23), i.e. exo-(1-->4)-beta-D-galactanase C12N9/2474Hyaluronoglucosaminidase (3.2.1.35), i.e. hyaluronidase C12N9/2477Hemicellulases not provided in a preceding group C12N9/248Xylanases C12N9/2482Endo-1,4-beta-xylanase (3.2.1.8) C12N9/2485Xylan endo-1,3-beta-xylosidase (3.2.1.32), i.e. endo-1,3-beta-xylanase C12N9/2488Mannanases C12N9/2491Beta-mannosidase (3.2.1.25), i.e. mannanase C12N9/2494Mannan endo-1,4-beta-mannosidase (3.2.1.78), i.e. endo-beta-mannanase C12N9/2497hydrolysing N- glycosyl compounds (3.2.2) C12N9/48acting on peptide bonds (3.4) C12N9/485Exopeptidases (3.4.11-3.4.19) C12N9/50Proteinases , e.g. Endopeptidases (3.4.21-3.4.25) C12N9/503derived from viruses C12N9/506derived from RNA viruses C12N9/52derived from bacteria or ArchaeaIn this group, Archaea, formerly known as Archaebacteria, are classified with bacteria. C12N9/54bacteria being Bacillus C12N9/58derived from fungi C12N9/60from yeast C12N9/62from Aspergillus C12N9/63derived from plants C12N9/64derived from animal tissue C12N9/6402from non-mammals C12N9/6405not being snakes C12N9/6408Serine endopeptidases (3.4.21) C12N9/641Cysteine endopeptidases (3.4.22) C12N9/6413Aspartic endopeptidases (3.4.23) C12N9/6416Metalloendopeptidases (3.4.24) C12N9/6418from snakes C12N9/6421from mammals C12N9/6424Serine endopeptidases (3.4.21) C12N9/6427Chymotrypsins (3.4.21.1; 3.4.21.2); Trypsin (3.4.21.4) C12N9/6429Thrombin (3.4.21.5) C12N9/6432Coagulation factor Xa (3.4.21.6) C12N9/6435Plasmin (3.4.21.7), i.e. fibrinolysin C12N9/6437Coagulation factor VIIa (3.4.21.21) C12N9/644Coagulation factor IXa (3.4.21.22) C12N9/6443Coagulation factor XIa (3.4.21.27) C12N9/6445Kallikreins (3.4.21.34; 3.4.21.35) C12N9/6448Elastases, e.g. pancreatic elastase (3.4.21.36); leukocyte elastase (3.4.31.37) C12N9/6451Coagulation factor XIIa (3.4.21.38) C12N9/6454Dibasic site splicing serine proteases, e.g. kexin (3.4.21.61); furin (3.4.21.75) and other proprotein convertases C12N9/6456Plasminogen activators C12N9/6459t-plasminogen activator (3.4.21.68), i.e. tPA C12N9/6462u-Plasminogen activator (3.4.21.73), i.e. urokinase C12N9/6464Protein C (3.4.21.69) C12N9/6467Granzymes, e.g. granzyme A (3.4.21.78); granzyme B (3.4.21.79) C12N9/647Blood coagulation factors not provided for in a preceding group or according to more than one of the proceeding groups C12N9/6472Cysteine endopeptidases (3.4.22) C12N9/6475Interleukin 1-beta convertase-like enzymes (3.4.22.10; 3.4.22.36; 3.4.22.63) C12N9/6478Aspartic endopeptidases (3.4.23) C12N9/6481Pepsins (3.4.23.1; 3.4.23.2; 3.4.23.3) C12N9/6483Chymosin (3.4.23.4), i.e. rennin C12N9/6486Renin (3.4.23.15) C12N9/6489Metalloendopeptidases (3.4.24) C12N9/6491Matrix metalloproteases [MMP's], e.g. interstitial collagenase (3.4.24.7); Stromelysins (3.4.24.17; 3.2.1.22); Matrilysin (3.4.24.23) C12N9/6494Neprilysin (3.4.24.11), i.e. enkephalinase or neutral-endopeptidase 24.11 C12N9/6497Endothelin-converting enzyme (3.4.24.71) C12N9/78acting on carbon to nitrogen bonds other than peptide bonds (3.5) C12N9/80acting on amide bonds in linear amides (3.5.1) C12N9/82Asparaginase (3.5.1.1) C12N9/84Penicillin amidase (3.5.1.11) C12N9/86acting on amide bonds in cyclic amides, e.g. penicillinase (3.5.2) C12N9/88Lyases (4.) C12N9/90Isomerases (5.) C12N9/92Glucose isomerase (5.3.1.5; 5.3.1.9; 5.3.1.18) C12N9/93Ligases (6) C12N9/94Pancreatin C12N9/96Stabilising an enzyme by forming an adduct or a compositionForming enzyme conjugates C12N9/98Preparation of granular or free-flowing enzyme compositions C12N9/96 takes precedence C12N9/99Enzyme inactivation by chemical treatment C12N11/00Carrier-bound or immobilised enzymesCarrier-bound or immobilised microbial cellsPreparation thereof C12N11/02Enzymes or microbial cells immobilised on or in an organic carrier C12N11/04entrapped within the carrier, e.g. gel or hollow fibres C12N11/06attached to the carrier via a bridging agent C12N11/08the carrier being a synthetic polymer C12N11/082obtained by reactions only involving carbon-to-carbon unsaturated bonds C12N11/084Polymers containing vinyl alcohol units C12N11/087Acrylic polymers C12N11/089obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds C12N11/091Phenol resinsAmino resins C12N11/093Polyurethanes C12N11/096PolyestersPolyamides C12N11/098formed in the presence of the enzymes or microbial cells C12N11/10the carrier being a carbohydrate C12N11/12Cellulose or derivatives thereof C12N11/14Enzymes or microbial cells immobilised on or in an inorganic carrier C12N11/16Enzymes or microbial cells immobilised on or in a biological cell C12N11/18Multi-enzyme systems C12N13/00Treatment of microorganisms or enzymes with electrical or wave energy, e.g. magnetism, sonic waves C12N15/00Mutation or genetic engineeringDNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purificationUse of hosts therefor mutants or genetically engineered microorganisms, per se C12N1/00, C12N5/00, C12N7/00; new plants per se A01H; plant reproduction by tissue culture techniques A01H4/00; new animals per se A01K67/00; use of medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases, gene therapy A61K48/00 C12N15/01Preparation of mutants without inserting foreign genetic material thereinScreening processes therefor C12N15/02Preparation of hybrid cells by fusion of two or more cells, e.g. protoplast fusion monoclonal antibodies C07K16/00; apparatus for cell fusion C12M C12N15/03Bacteria C12N15/04Fungi C12N15/09Recombinant DNA-technology C12N15/10Processes for the isolation, preparation or purification of DNA or RNA chemical preparation of DNA or RNA C07H21/00; preparation of non-structural polynucleotides from microorganisms or with enzymes C12P19/34In groups C12N15/10 - C12N15/1096, C-Sets are used for classification. The detailed information about the C-Sets construction and the associated syntax rules are found in the Definitions of C12N. C12N15/1003Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor C12N15/1006by means of a solid support carrier, e.g. particles, polymers C12N15/101by chromatography, e.g. electrophoresis, ion-exchange, reverse phase C12N15/1013by using magnetic beads C12N15/1017by filtration, e.g. using filters, frits, membranes C12N15/102Mutagenizing nucleic acids C12N15/1024In vivo mutagenesis using high mutation rate "mutator" host strains by inserting genetic material, e.g. encoding an error prone polymerase, disrupting a gene for mismatch repair C12N15/1027by DNA shuffling, e.g. RSR, STEP, RPR C12N15/1031mutagenesis by gene assembly, e.g. assembly by oligonucleotide extension PCR C12N15/1034Isolating an individual clone by screening libraries C12N15/1037Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display C12N15/1041Ribosome/Polysome display, e.g. SPERT, ARM C12N15/1044Preparation or screening of libraries displayed on scaffold proteins C12N15/1048SELEX C12N15/1051Gene trapping, e.g. exon-, intron-, IRES-, signal sequence-trap cloning, trap vectors C12N15/1055Protein x Protein interaction, e.g. two hybrid selection C12N15/1058Directional evolution of libraries, e.g. evolution of libraries is achieved by mutagenesis and screening or selection of mixed population of organisms C12N15/1062mRNA-Display, e.g. polypeptide and encoding template are connected covalently C12N15/1065Preparation or screening of tagged libraries, e.g. tagged microorganisms by STM-mutagenesis, tagged polynucleotides, gene tags C12N15/1068Template (nucleic acid) mediated chemical library synthesis, e.g. chemical and enzymatical DNA-templated organic molecule synthesis, libraries prepared by non ribosomal polypeptide synthesis [NRPS], DNA/RNA-polymerase mediated polypeptide synthesis C12N15/1072Differential gene expression library synthesis, e.g. subtracted libraries, differential screening C12N15/1075by coupling phenotype to genotype, not provided for in other groups of this subclass C12N15/1079Screening libraries by altering the phenotype or phenotypic trait of the host reporter assays C12N15/1086 C12N15/1082Preparation or screening gene libraries by chromosomal integration of polynucleotide sequences, HR-, site-specific-recombination, transposons, viral vectors C12N15/1086Preparation or screening of expression libraries, e.g. reporter assays C12N15/1089Design, preparation, screening or analysis of libraries using computer algorithms C12N15/1093General methods of preparing gene libraries, not provided for in other subgroups C12N15/1096cDNA Synthesis; Subtracted cDNA library construction, e.g. RT, RT-PCR C12N15/11DNA or RNA fragmentsModified forms thereof DNA or RNA not used in recombinant technology, C07H21/00Non-coding nucleic acids having a biological activity Documents relating to DNA or its corresponding RNA and their use in recombinant DNA technology or the preparation of specific peptides, e.g. enzymes, are classified in subclass C07K or in group C12N9/00 according to the peptides, with the appropriate indexing codes relating to their use in recombinant technology. Groups C12N15/11 - C12N15/117 cover also the use of non-coding nucleic acids as active ingredients in medicinal preparations. The C12N2303/00 ICO scheme has to be applied to these groups. When documents classifiable in one or more subgroups disclose general principles of the technology applicable to the whole field, classification is also made in group C12N15/111 C12N15/111General methods applicable to biologically active non-coding nucleic acids C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotidesAntisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing when used in plants C12N15/8218 C12N15/1131against viruses C12N15/1132against retroviridae, e.g. HIV C12N15/1133against herpetoviridae, e.g. HSV C12N15/1135against oncogenes or tumor suppressor genes C12N15/1136against growth factors, growth regulators, cytokines, lymphokines or hormones C12N15/1137against enzymes viral enzymes C12N15/1131; receptors C12N15/1138 C12N15/1138against receptors or cell surface proteins C12N15/115Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith ; Nucleic acids binding to non-nucleic acids, e.g. aptamers Aptamers fused to compounds which are already classified in groups C12N15/11 - C12N15/117, are classified with the corresponding compound C12N15/117Nucleic acids having immunomodulatory properties, e.g. containing CpG-motifs C12N15/52Genes encoding for enzymes or proenzymesIn this group genes encoding for proenzymes are classified with the corresponding genes encoding enzymes. C12N15/62DNA sequences coding for fusion proteins In this group, the following term is used with the meaning indicated: "fusion" means the fusion of two different proteins. C12N15/625containing a sequence coding for a signal sequence C12N15/63Introduction of foreign genetic material using vectorsVectorsUse of hosts thereforRegulation of expression C12N15/635Externally inducible repressor mediated regulation of gene expression, e.g. tetR inducible by tetracyline C12N15/64General methods for preparing the vector, for introducing it into the cell or for selecting the vector-containing hostIn the group C12N15/64, C-Sets are used for classification. The detailed information about the C-Sets construction and the associated syntax rules are found in the Definitions of C12N C12N15/65using markers enzymes used as markers C12N15/52In the group C12N15/65, C-Sets are used for classification. The detailed information about the C-Sets construction and the associated syntax rules are found in the Definitions of C12N C12N15/66General methods for inserting a gene into a vector to form a recombinant vector using cleavage and ligationUse of non-functional linkers or adaptors, e.g. linkers containing the sequence for a restriction endonuclease In this group, the following expression is used with the meaning indicated: "non-functional linkers" means DNA sequences which are used to link DNA sequences and which have no known function of structural gene or regulating function.In the group C12N15/66, C-Sets are used for classification. The detailed information about the C-Sets construction and the associated syntax rules are found in the Definitions of C12N C12N15/67General methods for enhancing the expression C12N15/68Stabilisation of the vector C12N15/69Increasing the copy number of the vector C12N15/70Vectors or expression systems specially adapted for E. coliThis group covers the use of E. coli as host.Shuttle vectors also replicating in E. coli are classified according to the other host. C12N15/71Expression systems using regulatory sequences derived from the trp-operon C12N15/72Expression systems using regulatory sequences derived from the lac-operon C12N15/73Expression systems using phage (lambda) regulatory sequences C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, MicromonosporaThis group covers the use of prokaryotes as hosts. C12N15/743for Agrobacterium; Rhizobium; Bradyrhizobium C12N15/746for lactic acid bacteria (Streptococcus; Lactococcus; Lactobacillus; Pediococcus; Enterococcus; Leuconostoc; Propionibacterium; Bifidobacterium; Sporolactobacillus) C12N15/75for Bacillus C12N15/76for Actinomycesfor Streptomyces C12N15/77for Corynebacteriumfor Brevibacterium C12N15/78for Pseudomonas C12N15/79Vectors or expression systems specially adapted for eukaryotic hostsThis group covers the use of eukaryotes as hosts. C12N15/80for fungi C12N15/81for yeasts C12N15/815for yeasts other than Saccharomyces C12N15/82for plant cells , e.g. plant artificial chromosomes (PACs)Documents are being continuously reclassified into this new classification scheme. See Warning notes below C12N15/8201Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation C12N15/8202by biological means, e.g. cell mediated or natural vector C12N15/8203Virus mediated transformation C12N15/8205Agrobacterium mediated transformation C12N15/8206by physical or chemical, i.e. non-biological, means, e.g. electroporation, PEG mediated C12N15/8207by mechanical means, e.g. microinjection, particle bombardment, silicon whiskers C12N15/8209Selection, visualisation of transformants, reporter constructs, e.g. antibiotic resistance markers Standard selectable markers such as neomycin phosphotransferase (NPT) are not systematically classified in C12N15/8209 C12N15/821Non-antibiotic resistance markers, e.g. morphogenetic, metabolic markers C12N15/8212Colour markers, e.g. beta-glucoronidase [GUS], green fluorescent protein [GFP], carotenoid C12N15/8213Targeted insertion of genes into the plant genome by homologous recombination C12N15/8214Plastid transformation C12N15/8216Methods for controlling, regulating or enhancing expression of transgenes in plant cells C12N15/8217Gene switch C12N15/8218Antisense, co-suppression, viral induced gene silencing [VIGS], post-transcriptional induced gene silencing [PTGS] C12N15/822Reducing position variability, e.g. by the use of scaffold attachment region/matrix attachment region (SAR/MAR); Use of SAR/MAR to regulate gene expression C12N15/8221Transit peptides C12N15/8222Developmentally regulated expression systems, tissue, organ specific, temporal or spatial regulation C12N15/8223Vegetative tissue-specific promoters C12N15/8225Leaf-specific, e.g. including petioles, stomata C12N15/8226Stem-specific, e.g. including tubers, beets C12N15/8227Root-specific C12N15/8229Meristem-specific, e.g. nodal, apical C12N15/823Reproductive tissue-specific promoters C12N15/8231Male-specific, e.g. anther, tapetum, pollen C12N15/8233Female-specific, e.g. pistil, ovule C12N15/8234Seed-specific, e.g. embryo, endosperm C12N15/8235Fruit-specific C12N15/8237Externally regulated expression systems C12N15/8238chemically inducible, e.g. tetracycline C12N15/8239pathogen inducible C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology C12N15/8242with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits C12N15/8243involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine C12N15/8245involving modified carbohydrate or sugar alcohol metabolism, e.g. starch biosynthesis C12N15/8246Non-starch polysaccharides, e.g. cellulose, fructans, levans C12N15/8247involving modified lipid metabolism, e.g. seed oil composition C12N15/8249involving ethylene biosynthesis, senescence or fruit development, e.g. modified tomato ripening, cut flower shelf-life C12N15/825involving pigment biosynthesisTransgenic plants with altered flower morphology are also classified in this group C12N15/8251Amino acid content, e.g. synthetic storage proteins, altering amino acid biosynthesis C12N15/8253Methionine or cysteine C12N15/8254Tryptophan or lysine C12N15/8255involving lignin biosynthesis C12N15/8257for the production of primary gene products, e.g. pharmaceutical products, interferon C12N15/8258for the production of oral vaccines (antigens) or immunoglobulins C12N15/8259Phytoremediation C12N15/8261with agronomic (input) traits, e.g. crop yield C12N15/8262involving plant development C12N15/8263Ablation; Apoptosis C12N15/8265Transgene containment, e.g. gene dispersal C12N15/8266Abscission; Dehiscence; Senescence C12N15/8267Seed dormancy, germination or sprouting C12N15/8269Photosynthesis C12N15/827Flower development or morphology, e.g. flowering promoting factor [FPF] C12N15/8271for stress resistance, e.g. heavy metal resistance C12N15/8273for drought, cold, salt resistance C12N15/8274for herbicide resistance C12N15/8275Glyphosate C12N15/8277Phosphinotricin C12N15/8278Sulfonylurea C12N15/8279for biotic stress resistance, pathogen resistance, disease resistance C12N15/8281for bacterial resistance C12N15/8282for fungal resistance C12N15/8283for virus resistance C12N15/8285for nematode resistance C12N15/8286for insect resistance C12N15/8287for fertility modification, e.g. apomixis C12N15/8289Male sterility C12N15/829Female sterility C12N15/8291Hormone-influenced development C12N15/8293Abscisic acid [ABA] C12N15/8294Auxins C12N15/8295Cytokinins C12N15/8297Gibberellins; GA3 C12N15/8298Brassinosteroids C12N15/85for animal cells C12N15/8509for producing genetically modified animals, e.g. transgenicAdditional aspects of the modified animals are classified in the groups A01K2207/00 - A01K2267/00 C12N2015/8518expressing industrially exogenous proteins, e.g. for pharmaceutical use, human insulin, blood factors, immunoglobulins, pseudoparticles C12N2015/8527for producing animal models, e.g. for tests or diseases C12N2015/8536Animal models for genetic diseases C12N2015/8545for Alzheimer''s disease C12N2015/8554Invertebrates models for Alzheimer''s disease C12N2015/8563for autoimmune diseases, e.g. Insulin-dependent diabetes mellitus C12N2015/8572Animal models for proliferative diseases, e.g. comprising an oncogene C12N2015/8581Animal models for infectious diseases, e.g. AIDS C12N2015/859Animal models comprising reporter system for screening tests C12N15/86Viral vectors From 2012-03-15 groups C12N15/861 - C12N15/869 and subgroups thereof are no longer used for the classification of new documents. The documents in these (sub)groups are being reclassified to the corresponding codes in the range C12N2710/00-C12N2795/00 C12N15/861Adenoviral vectors C12N15/8613Chimaeric vector systems comprising heterologous sequences for production of another viral vector C12N15/8616Special methods for targeting systems C12N15/863Poxviral vectors, e.g. entomopoxvirus C12N15/8633Avian poxviral vectors C12N15/8636Vaccina virus vectors C12N15/864Parvoviral vectors , e.g. parvovirus, densovirus C12N15/8645Adeno-associated virus C12N15/866Baculoviral vectors C12N15/867Retroviral vectors C12N15/8673Special methods for packaging systems C12N15/8676Special methods for targeting systems C12N15/869Herpesviral vectors C12N15/8695Herpes simplex virus-based vectors C12N15/87Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation C12N15/873Techniques for producing new embryos, e.g. nuclear transfer, manipulation of totipotent cells or production of chimeric embryos C12N15/877Techniques for producing new mammalian cloned embryos C12N15/8771Bovine embryos C12N15/8772Caprine embryos C12N15/8773Ovine embryos C12N15/8775Murine embryos C12N15/8776Primate embryos C12N15/8777Rabbit embryos C12N15/8778Swine embryos C12N15/88using microencapsulation, e.g. using amphiphile liposome vesicle C12N15/89using microinjection C12N15/895using biolistic methods C12N15/90Stable introduction of foreign DNA into chromosome C12N15/902using homologous recombination C12N15/905in yeast C12N15/907in mammalian cells C12N2303/00 C12N2303/00Indexing codes associated with general methodologies in the field of biologically active non-coding nucleic acids
Indexing codes of group C12N2303/00 are only used in combination with group C12N15/111
C12N2310/00Structure or type of the nucleic acidIn groups C12N2310/00 - C12N2310/533, C-Sets are used for classification. The detailed information about the C-Sets construction and the associated syntax rules are found in the Definitions of C12N. C12N2310/10Type of nucleic acid C12N2310/11Antisense C12N2310/111spanning the whole gene, or a large part of it C12N2310/113targeting other non-coding nucleic acids, e.g. antagomirs C12N2310/12catalytic nucleic acids, e.g. ribozymes C12N2310/121Hammerhead C12N2310/122Hairpin C12N2310/123Hepatitis delta C12N2310/124based on group I or II introns C12N2310/1241Tetrahymena C12N2310/126involving RNAse P C12N2310/127DNAzymes C12N2310/128processing or releasing ribozyme C12N2310/13Decoys C12N2310/14interfering N.A. C12N2310/141MicroRNAs, miRNAs C12N2310/15Nucleic acids forming more than 2 strands, e.g. TFOs C12N2310/151more than 3 strands, e.g. tetrads, H-DNA C12N2310/152on a single-stranded target, e.g. fold-back TFOs C12N2310/153with the aid of a protein, e.g. recombinase C12N2310/16Aptamers C12N2310/17Immunomodulatory nucleic acids C12N2310/18acting by a non-sequence specific mechanism other than C12N2310/16 or C12N2310/17 C12N2310/20involving clustered regularly interspaced short palindromic repeats [CRISPRs] C12N2310/30Chemical structure C12N2310/31of the backbone C12N2310/311Phosphotriesters C12N2310/312Phosphonates C12N2310/3125Methylphosphonates C12N2310/313Phosphorodithioates C12N2310/314Phosphoramidates C12N2310/3145with the nitrogen in 3' or 5'-position C12N2310/315Phosphorothioates C12N2310/316Phosphonothioates C12N2310/317with an inverted bond, e.g. a cap structure C12N2310/318where the PO2 is completely replaced, e.g. MMI or formacetal C12N2310/3181Peptide nucleic acid, PNA C12N2310/3183Diol linkers, e.g. glycols or propanediols C12N2310/319linked by 2'-5' linkages, i.e. having a free 3'-position C12N2310/32of the sugar C12N2310/3212'-O-R Modification C12N2310/3222'-R Modification C12N2310/323modified ring structure C12N2310/3231having an additional ring, e.g. LNA, ENA C12N2310/3233Morpholino-type ring C12N2310/3235having the O of the ribose replaced by another atom C12N2310/33of the base C12N2310/331Universal or degenerate base C12N2310/332Abasic residue C12N2310/333Modified A C12N2310/334Modified C C12N2310/33415-Methylcytosine C12N2310/335Modified T or U C12N2310/336Modified G C12N2310/337in alpha-anomeric form C12N2310/34Spatial arrangement of the modifications C12N2310/341Gapmers, i.e. of the type ===---=== C12N2310/342Hemimers, i.e. of the type ====---- C12N2310/343having patterns, e.g. ==--==--==-- C12N2310/344Position-specific modifications, e.g. on every purine, at the 3'-end C12N2310/345having at least two different backbone modifications C12N2310/346having a combination of backbone and sugar modifications C12N2310/35Nature of the modification C12N2310/351Conjugate C12N2310/3511intercalating or cleaving agent C12N2310/3513ProteinPeptide C12N2310/3515Lipophilic moiety, e.g. cholesterol C12N2310/3517MarkerTag C12N2310/3519Fusion with another nucleic acid C12N2310/352linked to the nucleic acid via a carbon atom C12N2310/3521Methyl C12N2310/3523Allyl C12N2310/3525MOE, methoxyethoxy C12N2310/3527Other alkyl chain C12N2310/3529Aromatic substituent C12N2310/353linked to the nucleic acid via an atom other than carbon C12N2310/3531Hydrogen C12N2310/3533Halogen C12N2310/3535Nitrogen C12N2310/50Physical structure C12N2310/51in polymeric form, e.g. multimers, concatemers C12N2310/52branched C12N2310/53partially self-complementary or closed C12N2310/531Stem-loopHairpin C12N2310/532Closed or circular C12N2310/533having a mismatch or nick in at least one of the strands C12N2320/00ApplicationsUses C12N2320/10in screening processes C12N2320/11for the determination of target sites, i.e. of active nucleic acids C12N2320/12in functional genomics, i.e. for the determination of gene function C12N2320/13in a process of directed evolution, e.g. SELEX, acquiring a new function C12N2320/30Special therapeutic applications C12N2320/31Combination therapy C12N2320/32Special delivery means, e.g. tissue-specific C12N2320/33Alteration of splicing C12N2320/34Allele or polymorphism specific uses C12N2320/35based on a specific dosage / administration regimen C12N2320/50Methods for regulating/modulating their activity C12N2320/51modulating the chemical stability, e.g. nuclease-resistance C12N2320/52modulating the physical stability, e.g. GC-content C12N2320/53reducing unwanted side-effects C12N2330/00Production C12N2330/10naturally occurring C12N2330/30chemically synthesised C12N2330/31Libraries, arrays C12N2330/50Biochemical production, i.e. in a transformed host cell C12N2330/51Specially adapted vectors C12N2500/00Specific components of cell culture medium C12N2500/02Atmosphere, e.g. low oxygen conditions C12N2500/05Inorganic components C12N2500/10MetalsMetal chelators cobalamine C12N2500/38 C12N2500/12Light metals, i.e. alkali, alkaline earth, Be, Al, Mg C12N2500/14CalciumCa chelatorsCalcitonin C12N2500/16MagnesiumMg chelators C12N2500/20Transition metals C12N2500/22ZincZn chelators insulin-zinc complexes C12N2501/33 C12N2500/24IronFe chelatorsTransferrin C12N2500/25Insulin-transferrinInsulin-transferrin-selenium C12N2500/30Organic components metal chelators C12N2500/10; calcitonin C12N2500/14; transferrin C12N2500/24 C12N2500/32Amino acids C12N2500/33other than alpha-amino carboxylic acids, e.g. beta-amino acids, taurine C12N2500/34Sugars C12N2500/35Polyols, e.g. glycerin, inositol C12N2500/36Lipids C12N2500/38Vitamins C12N2500/40Nucleotides, nucleosides, bases cyclic nucleotides C12N2501/01, anti-neoplasic drugs C12N2501/06 C12N2500/42Organic phosphate, e.g. beta glycerophosphate C12N2500/44Thiols, e.g. mercaptoethanol C12N2500/46Amines, e.g. putrescine C12N2500/50Soluble polymers, e.g. polyethyleneglycol [PEG] C12N2500/60Buffer, e.g. pH regulation, osmotic pressure C12N2500/62DMSO C12N2500/70Undefined extracts conditioned medium C12N2502/00 C12N2500/72from bacteria C12N2500/74from fungi, e.g. yeasts C12N2500/76from plants C12N2500/78from protozoa C12N2500/80from animals C12N2500/82from invertebrates C12N2500/84from mammals C12N2500/90Serum-free medium, which may still contain naturally-sourced components C12N2500/92Medium free of human- or animal-derived components C12N2500/95Protein-free medium and culture conditions C12N2500/98Xeno-free medium and culture conditions C12N2500/99Serum-free medium This group is no longer used for the classification of new documents as from 2012-01-01. The backlog of this group is being continuously reclassified to C12N2500/90 - C12N2500/98 C12N2501/00Active agents used in cell culture processes, e.g. differentationWhenever possible, indexation is done by signalling pathway and not by chemical structure, e.g. the group of a protein covers not only peptide analogs of it and the corresponding nucleic acids, as in C07K14/00, but also antibodies, anti-idiotypic antibodies, non-peptide ligands of the receptor, the receptor itself, antibodies against the receptor or inhibitors of the conversion enzyme which processes the protein precursor. Unless otherwise provided for, ligands and substrates take precedence over receptors and enzymes. C12N2501/01Modulators of cAMP or cGMP, e.g. non-hydrolysable analogs, phosphodiesterase inhibitors, cholera toxin C12N2501/02Compounds of the arachidonic acid pathway, e.g. prostaglandins, leukotrienes C12N2501/03Compounds acting on the NO pathway, e.g. nitrososarginine C12N2501/04Immunosuppressors, e.g. cyclosporin, tacrolimus C12N2501/05Adjuvants C12N2501/051Lipid A (MPA, MPL) C12N2501/052Lipopolysaccharides [LPS] C12N2501/054Muramyle peptides C12N2501/056Immunostimulating oligonucleotides, e.g. CpG C12N2501/06Anti-neoplasic drugs, anti-retroviral drugs, e.g. azacytidine, cyclophosphamide C12N2501/065Modulators of histone acetylation C12N2501/07Heat shock proteins C12N2501/10Growth factors C12N2501/105Insulin-like growth factors [IGF] C12N2501/11Epidermal growth factor [EGF] C12N2501/113Acidic fibroblast growth factor (aFGF, FGF-1) C12N2501/115Basic fibroblast growth factor (bFGF, FGF-2) C12N2501/117Keratinocyte growth factors (KGF-1, i.e. FGF-7; KGF-2, i.e. FGF-12) C12N2501/119Other fibroblast growth factors, e.g. FGF-4, FGF-8, FGF-10 C12N2501/12Hepatocyte growth factor [HGF] C12N2501/125Stem cell factor [SCF], c-kit ligand [KL] C12N2501/13Nerve growth factor [NGF]Brain-derived neurotrophic factor [BDNF]Cilliary neurotrophic factor [CNTF]Glial-derived neurotrophic factor [GDNF]Neurotrophins [NT]Neuregulins C12N2501/135Platelet-derived growth factor [PDGF] C12N2501/14Erythropoietin [EPO] C12N2501/145Thrombopoietin [TPO] C12N2501/148Transforming growth factor alpha [TGF-a] C12N2501/15Transforming growth factor beta (TGF-β) C12N2501/155Bone morphogenic proteins [BMP]OsteogeninsOsteogenic factorBone inducing factor C12N2501/16ActivinInhibinMullerian inhibiting substance C12N2501/165Vascular endothelial growth factor [VEGF] C12N2501/17Angiopoietin C12N2501/175Cardiotrophin C12N2501/18Liver cell growth factor (LCGF, Gly-His-Lys) C12N2501/185OsteoprotegerinOsteoclast differentiation factor (ODF, RANKL) C12N2501/19Growth and differentiation factors [GDF] C12N2501/195Heregulin, neu differentiation factor C12N2501/20CytokinesChemokines C12N2501/21Chemokines, e.g. MIP-1, MIP-2, RANTES, MCP, PF-4 C12N2501/22Colony stimulating factors (G-CSF, GM-CSF) C12N2501/23Interleukins [IL] C12N2501/2301Interleukin-1 (IL-1) C12N2501/2302Interleukin-2 (IL-2) C12N2501/2303Interleukin-3 (IL-3) C12N2501/2304Interleukin-4 (IL-4) C12N2501/2305Interleukin-5 (IL-5) C12N2501/2306Interleukin-6 (IL-6) C12N2501/2307Interleukin-7 (IL-7) C12N2501/2308Interleukin-8 (IL-8) C12N2501/2309Interleukin-9 (IL-9) C12N2501/231Interleukin-10 (IL-10) C12N2501/2311Interleukin-11 (IL-11) C12N2501/2312Interleukin-12 (IL-12) C12N2501/2313Interleukin-13 (IL-13) C12N2501/2314Interleukin-14 (IL-14) C12N2501/2315Interleukin-15 (IL-15) C12N2501/2316Interleukin-16 (IL-16) C12N2501/2317Interleukin-17 (IL-17) C12N2501/2318Interleukin-18 (IL-18) C12N2501/2319Interleukin-19 (IL-19) C12N2501/232Interleukin-20 (IL-20) C12N2501/2321Interleukin-21 (IL-21) C12N2501/2322Interleukin-22 (IL-22) C12N2501/2323Interleukin-23 (IL-23) C12N2501/2324Interleukin-24 (IL-24) C12N2501/2325Interleukin-25 (IL-25) C12N2501/2326Interleukin-26 (IL-26) C12N2501/2327Interleukin-27 (IL-27) C12N2501/2328Interleukin-28 (IL-28) C12N2501/2329Interleukin-29 (IL-29) C12N2501/233Interleukin-30 (IL-30) C12N2501/2331Interleukin-31 (IL-31) C12N2501/2332Interleukin-32 (IL-32) C12N2501/2333Interleukin-33 (IL-33) C12N2501/2334Interleukin-34 (IL-34) C12N2501/2335Interleukin-35 (IL-35) C12N2501/235Leukemia inhibitory factor [LIF] C12N2501/237Oncostatin M [OSM] C12N2501/24Interferons [IFN] C12N2501/25Tumour necrosing factors [TNF] C12N2501/26Flt-3 ligand (CD135L, flk-2 ligand) C12N2501/30Hormones derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin C12N2501/85 C12N2501/305Growth hormone [GH], aka. somatotropin C12N2501/31Pituitary sex hormones, e.g. follicle-stimulating hormone [FSH], luteinising hormone [LH]Chorionic gonadotropins C12N2501/315Prolactin C12N2501/32Angiotensins [AT], angiotensinogen C12N2501/33Insulin together with transferrin C12N2500/25; Insulin-like growth factors C12N2501/105 C12N2501/335GlucagonGlucagon-like peptide [GLP]Exendin C12N2501/34CalcitoninCalcitonin-gene related peptide [CGRO]Amylin C12N2501/345GastrinCholecystokinins [CCK] C12N2501/35Vasoactive intestinal peptide [VIP]Pituitary adenylate cyclase activating polypeptide [PACAP] C12N2501/355Leptin C12N2501/36Somatostatin C12N2501/365Endothelin C12N2501/37Parathyroid hormone [PTH] C12N2501/375Thyroid stimulating hormone [TSH] C12N2501/38with nuclear receptors C12N2501/385of the family of the retinoic acid recptor, e.g. RAR, RXRPeroxisome proliferator-activated receptor [PPAR] C12N2501/39Steroid hormones C12N2501/392Sexual steroids C12N2501/395Thyroid hormones C12N2501/40Regulators of development C12N2501/405Cell cycle regulated proteins, e.g. cyclins, cyclin-dependant kinases C12N2501/41Hedgehog proteinsCyclopamine (inhibitor) C12N2501/415WntFrizzeled C12N2501/42NotchDeltaJaggedSerrate C12N2501/48Regulators of apoptosis C12N2501/50Cell markersCell surface determinants C12N2501/505CD4CD8 C12N2501/51B7 molecules, e.g. CD80, CD86, CD28 (ligand), CD152 (ligand) C12N2501/515CD3, T-cell receptor complex C12N2501/52CD40, CD40-ligand (CD154) C12N2501/53CD2 C12N2501/58Adhesion molecules, e.g. ICAM, VCAM, CD18 (ligand), CD11 (ligand), CD49 (ligand) C12N2501/585Integrins C12N2501/59Lectins C12N2501/599with CD designations not provided for elsewhere C12N2501/60Transcription factors C12N2501/602Sox-2 C12N2501/603Oct-3/4 C12N2501/604Klf-4 C12N2501/605Nanog C12N2501/606c-Myc C12N2501/608Lin28 C12N2501/65MicroRNA C12N2501/70Enzymes C12N2501/71Oxidoreductases (EC 1.) C12N2501/72Transferases (EC 2.) acetylation of histones C12N2501/065 C12N2501/724Glycosyltransferases (EC 2.4.) C12N2501/727Kinases (EC 2.7.) C12N2501/73Hydrolases (EC 3.) C12N2501/734Proteases (EC 3.4.) C12N2501/80NeurotransmittersNeurohormones C12N2501/805Acetylcholine C12N2501/81Adrenaline C12N2501/815Dopamine C12N2501/82Histamine C12N2501/825Serotonine (5-HT)Melatonine C12N2501/83Tachykinins, e.g. substance P C12N2501/835Neuropeptide Y [NPY]Peptide YY [PYY] C12N2501/84Excitatory amino acids C12N2501/845Gamma amino butyric acid [GABA] C12N2501/85Hormones derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin C12N2501/855Corticotropin [ACTH] C12N2501/86Melanocyte-stimulating hormone [MSH] C12N2501/90Polysaccharides C12N2501/905Hyaluronic acid C12N2501/91Heparin C12N2501/998Proteins not provided for elsewhereClassification by pathway does not apply. C12N2501/999Small molecules not provided for elsewhereClassification by pathway does not apply. C12N2502/00Coculture withConditioned medium produced by C12N2502/02embryonic cells C12N2502/025extra-embryonic cells, e.g. amniotic epithelium, placental cells, Wharton's jelly C12N2502/03non-embryonic pluripotent stem cells C12N2502/04germ cells C12N2502/07endocrine cells C12N2502/072adrenal cells C12N2502/074pinealocytes C12N2502/076pituitary cells C12N2502/078thyroid, parathyroid cells C12N2502/08cells of the nervous system C12N2502/081neurons C12N2502/083sensory transducers C12N2502/085eye cells C12N2502/086glial cells C12N2502/088neural stem cells C12N2502/09epidermal cells, skin cells, oral mucosa cells C12N2502/091melanocytes C12N2502/092hair cells C12N2502/094keratinocytes C12N2502/095mammary cells C12N2502/097oral mucosa cells C12N2502/098cells of secretory glands, e.g. parotid gland, salivary glands, sweat glands, lacrymal glands C12N2502/11blood or immune system cells C12N2502/1107B cells C12N2502/1114T cells C12N2502/1121Dendritic cells C12N2502/1128Erythrocytes C12N2502/1135Granulocytes C12N2502/1142Osteoclasts C12N2502/115Platelets, megakaryocytes C12N2502/1157Monocytes, macrophages C12N2502/1164NK cells C12N2502/1171Haematopoietic stem cells C12N2502/1178Spleen cells C12N2502/1185Thymus cells C12N2502/1192Lymphatic cells C12N2502/13connective tissue cellsgeneric mesenchyme cells, e.g. so-called "embryonic fibroblasts" C12N2502/1305Adipocytes C12N2502/1311Osteocytes, osteoblasts, odontoblasts C12N2502/1317Chondrocytes C12N2502/1323Adult fibroblasts C12N2502/1329Cardiomyocytes C12N2502/1335Skeletal muscle cells, myocytes, myoblasts, myotubes C12N2502/1341Tenocytes, cells from tendons and ligaments C12N2502/1347Smooth muscle cells C12N2502/1352Mesenchymal stem cells C12N2502/1358Bone marrow mesenchymal stem cells (BM-MSC) C12N2502/1364Dental pulp stem cells, dental follicle stem cells C12N2502/137Blood-borne mesenchymal stem cells, e.g. Msc from umbilical cord blood C12N2502/1376Mesenchymal stem cells from hair follicles C12N2502/1382Adipose-derived stem cells [ADSC], adipose stromal stem cells C12N2502/1388Mesenchymal stem cells from other natural sources C12N2502/1394Bone marrow stromal cellswhole marrow C12N2502/14hepatocytes C12N2502/22pancreatic cells C12N2502/23Gastro-intestinal tract cells C12N2502/24Genital tract cells, non-germinal cells from gonads C12N2502/243Cells of the female genital tract, non-germinal ovarian cells C12N2502/246Cells of the male genital tract, non-germinal testis cells C12N2502/25Urinary tract cells, renal cells C12N2502/253Bladder cells C12N2502/256Renal cells C12N2502/27Lung cells, respiratory tract cells C12N2502/28Vascular endothelial cells C12N2502/30tumour cells C12N2502/45Artificially induced pluripotent stem cells C12N2502/50invertebrate cells C12N2502/70Non-animal cells C12N2502/99genetically modified cellsUse C12N2501/00 to index the expressed products. C12N2503/00Use of cells in diagnostics C12N2503/02Drug screening C12N2503/04Screening or testing on artificial tissues C12N2503/06Screening or testing on artificial skin C12N2506/00Differentiation of animal cells from one lineage to anotherDifferentiation of pluripotent cells This scheme indexes the starting point of a differentiation process and is used in combination with classification in C12N5/06 for the end product. Differentiation of a restricted progenitor cell into its expected progeny is not indexed. Differentiation of totipotent cells and dedifferentiation are always indexed. C12N2506/02from embryonic cells C12N2506/025from extra-embryonic cells, e.g. trophoblast, placenta C12N2506/03from non-embryonic pluripotent stem cells C12N2506/04from germ cells C12N2506/07from endocrine cells C12N2506/072from adrenal cells C12N2506/074from pinealocytes C12N2506/076from pituitary cells C12N2506/078from thyroid, parathyroid cells C12N2506/08from cells of the nervous system C12N2506/09from epidermal cells, from skin cells, from oral mucosa cells C12N2506/091from melanocytes C12N2506/092from hair cells C12N2506/094from keratinocytes C12N2506/095from mammary cells C12N2506/097from oral mucosa cells C12N2506/098from cells of secretory glands, e.g. parotid gland, salivary glands, sweat glands, lacrymal glands C12N2506/11from blood or immune system cells C12N2506/115from monocytes, from macrophages C12N2506/13from connective tissue cells, from mesenchymal cells C12N2506/1307from adult fibroblasts C12N2506/1315from cardiomyocytes C12N2506/1323from skeletal muscle cells C12N2506/133from tenocytes C12N2506/1338from smooth muscle cells C12N2506/1346from mesenchymal stem cells C12N2506/1353from bone marrow mesenchymal stem cells (BM-MSC) C12N2506/1361from dental pulp or dental follicle stem cells C12N2506/1369from blood-borne mesenchymal stem cells, e.g. MSC from umbilical blood C12N2506/1376from mesenchymal stem cells derived from hair follicles C12N2506/1384from adipose-derived stem cells [ADSC], from adipose stromal stem cells C12N2506/1392from mesenchymal stem cells from other natural sources C12N2506/14from hepatocytes C12N2506/22from pancreatic cells C12N2506/23from cells of the gastro-intestinal tract C12N2506/24from cells of the genital tract, from non-germinal gonad cells C12N2506/243from cells of the female genital tract cells, from non-germinal ovarian cells C12N2506/246from cells of the male genital tract cells, from non-germinal testis cells C12N2506/25from renal cells, from cells of the urinary tract C12N2506/27from lung cells, from cells of the respiratory tract C12N2506/28from vascular endothelial cells C12N2506/30from cancer cells, e.g. reversion of tumour cells Unless the tumourigenic phenotype is totally reversed, the end product is still classified under C12N5/0693. C12N2506/45from artificially induced pluripotent stem cells C12N2509/00Methods for the dissociation of cells, e.g. specific use of enzymes C12N2509/10Mechanical dissociation C12N2510/00Genetically modified cells C12N2510/02Cells for production C12N2510/04Immortalised cells C12N2511/00Cells for large scale production C12N2513/003D culture C12N2517/00Cells related to new breeds of animals C12N2517/02Cells from transgenic animals C12N2517/04Cells produced using nuclear transfer C12N2517/10Conditioning of cells for in vitro fecondation or nuclear transfer C12N2521/00Culture process characterised by the use of hydrostatic pressure, flow or shear forces C12N2521/10Sound, e.g. ultrasounds C12N2523/00Culture process characterised by temperature C12N2525/00Culture process characterised by gravity, e.g. microgravity C12N2527/00Culture process characterised by the use of mechanical forces, e.g. strain, vibration C12N2529/00Culture process characterised by the use of electromagnetic stimulation C12N2529/10Stimulation by light C12N2531/00Microcarriers C12N2533/00Supports or coatings for cell culture, characterised by material C12N2533/10Mineral substrates C12N2533/12Glass C12N2533/14Ceramic C12N2533/18Calcium salts, e.g. apatite, Mineral components from bones, teeth, shells C12N2533/20Small organic molecules C12N2533/30Synthetic polymers thermoreactive polymers, e.g. PNIPAm, C12N2539/10 C12N2533/32Polylysine, polyornithine C12N2533/40Polyhydroxyacids, e.g. polymers of glycolic or lactic acid (PGA, PLA, PLGA)Bioresorbable polymers C12N2533/50Proteins C12N2533/52FibronectinLaminin C12N2533/54CollagenGelatin C12N2533/56FibrinThrombin C12N2533/70Polysaccharides C12N2533/72Chitin, chitosan C12N2533/74Alginate C12N2533/76Agarose, agar-agar C12N2533/78Cellulose C12N2533/80Hyaluronan C12N2533/90Substrates of biological origin, e.g. extracellular matrix, decellularised tissue C12N2533/92AmnionDecellularised dermis or mucosa C12N2535/00Supports or coatings for cell culture characterised by topography C12N2535/10Patterned coating C12N2537/00Supports and/or coatings for cell culture characterised by physical or chemical treatment C12N2537/10Cross-linking C12N2539/00Supports and/or coatings for cell culture characterised by properties C12N2539/10Coating allowing for selective detachment of cells, e.g. thermoreactive coating
C12N2710/00Viruses C12N2710/00dsDNA viruses C12N2710/00011Details C12N2710/00021Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2710/00022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2710/00023Virus like particles [VLP] C12N2710/00031Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2710/00032Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2710/00033Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory C12N2710/00034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein C12N2710/00041Use of virus, viral particle or viral elements as a vector C12N2710/00042virus or viral particle as vehicle, e.g. encapsulating small organic molecule C12N2710/00043viral genome or elements thereof as genetic vector C12N2710/00044Chimeric viral vector comprising heterologous viral elements for production of another viral vector C12N2710/00045Special targeting system for viral vectors C12N2710/00051Methods of production or purification of viral material C12N2710/00052relating to complementing cells and packaging systems for producing virus or viral particles C12N2710/00061Methods of inactivation or attenuation C12N2710/00062by genetic engineering C12N2710/00063by chemical treatment C12N2710/00064by serial passage C12N2710/00071Demonstrated in vivo effect C12N2710/00088for redistribution C12N2710/10011Adenoviridae C12N2710/10021Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2710/10022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2710/10023Virus like particles [VLP] C12N2710/10031Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2710/10032Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2710/10033Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory C12N2710/10034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein C12N2710/10041Use of virus, viral particle or viral elements as a vector C12N2710/10042virus or viral particle as vehicle, e.g. encapsulating small organic molecule C12N2710/10043viral genome or elements thereof as genetic vector C12N2710/10044Chimeric viral vector comprising heterologous viral elements for production of another viral vector C12N2710/10045Special targeting system for viral vectors C12N2710/10051Methods of production or purification of viral material C12N2710/10052relating to complementing cells and packaging systems for producing virus or viral particles C12N2710/10061Methods of inactivation or attenuation C12N2710/10062by genetic engineering C12N2710/10063by chemical treatment C12N2710/10064by serial passage C12N2710/10071Demonstrated in vivo effect C12N2710/10088for redistribution C12N2710/10111Atadenovirus, e.g. ovine adenovirus D C12N2710/10121Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2710/10122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2710/10123Virus like particles [VLP] C12N2710/10131Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2710/10132Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2710/10133Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory C12N2710/10134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein C12N2710/10141Use of virus, viral particle or viral elements as a vector C12N2710/10142virus or viral particle as vehicle, e.g. encapsulating small organic molecule C12N2710/10143viral genome or elements thereof as genetic vector C12N2710/10144Chimeric viral vector comprising heterologous viral elements for production of another viral vector C12N2710/10145Special targeting system for viral vectors C12N2710/10151Methods of production or purification of viral material C12N2710/10152relating to complementing cells and packaging systems for producing virus or viral particles C12N2710/10161Methods of inactivation or attenuation C12N2710/10162by genetic engineering C12N2710/10163by chemical treatment C12N2710/10164by serial passage C12N2710/10171Demonstrated in vivo effect C12N2710/10188for redistribution C12N2710/10211Aviadenovirus, e.g. fowl adenovirus A C12N2710/10221Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2710/10222New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2710/10223Virus like particles [VLP] C12N2710/10231Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2710/10232Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2710/10233Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory C12N2710/10234Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein C12N2710/10241Use of virus, viral particle or viral elements as a vector C12N2710/10242virus or viral particle as vehicle, e.g. encapsulating small organic molecule C12N2710/10243viral genome or elements thereof as genetic vector C12N2710/10244Chimeric viral vector comprising heterologous viral elements for production of another viral vector C12N2710/10245Special targeting system for viral vectors C12N2710/10251Methods of production or purification of viral material C12N2710/10252relating to complementing cells and packaging systems for producing virus or viral particles C12N2710/10261Methods of inactivation or attenuation C12N2710/10262by genetic engineering C12N2710/10263by chemical treatment C12N2710/10264by serial passage C12N2710/10271Demonstrated in vivo effect C12N2710/10288for redistribution C12N2710/10311Mastadenovirus, e.g. human or simian adenoviruses C12N2710/10321Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2710/10322New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2710/10323Virus like particles [VLP] C12N2710/10331Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2710/10332Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2710/10333Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory C12N2710/10334Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein C12N2710/10341Use of virus, viral particle or viral elements as a vector C12N2710/10342virus or viral particle as vehicle, e.g. encapsulating small organic molecule C12N2710/10343viral genome or elements thereof as genetic vector C12N2710/10344Chimeric viral vector comprising heterologous viral elements for production of another viral vector C12N2710/10345Special targeting system for viral vectors C12N2710/10351Methods of production or purification of viral material C12N2710/10352relating to complementing cells and packaging systems for producing virus or viral particles C12N2710/10361Methods of inactivation or attenuation C12N2710/10362by genetic engineering C12N2710/10363by chemical treatment C12N2710/10364by serial passage C12N2710/10371Demonstrated in vivo effect C12N2710/10388for redistribution C12N2710/12011Asfarviridae C12N2710/12021Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2710/12022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2710/12023Virus like particles [VLP] C12N2710/12031Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2710/12032Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2710/12033Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory C12N2710/12034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein C12N2710/12041Use of virus, viral particle or viral elements as a vector C12N2710/12042virus or viral particle as vehicle, e.g. encapsulating small organic molecule C12N2710/12043viral genome or elements thereof as genetic vector C12N2710/12044Chimeric viral vector comprising heterologous viral elements for production of another viral vector C12N2710/12045Special targeting system for viral vectors C12N2710/12051Methods of production or purification of viral material C12N2710/12052relating to complementing cells and packaging systems for producing virus or viral particles C12N2710/12061Methods of inactivation or attenuation C12N2710/12062by genetic engineering C12N2710/12063by chemical treatment C12N2710/12064by serial passage C12N2710/12071Demonstrated in vivo effect C12N2710/12088for redistribution C12N2710/14011Baculoviridae C12N2710/14021Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2710/14022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2710/14023Virus like particles [VLP] C12N2710/14031Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2710/14032Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2710/14033Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory C12N2710/14034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein C12N2710/14041Use of virus, viral particle or viral elements as a vector C12N2710/14042virus or viral particle as vehicle, e.g. encapsulating small organic molecule C12N2710/14043viral genome or elements thereof as genetic vectore C12N2710/14044Chimeric viral vector comprising heterologous viral elements for production of another viral vector C12N2710/14045Special targeting system for viral vectors C12N2710/14051Methods of production or purification of viral material C12N2710/14052relating to complementing cells and packaging systems for producing virus or viral particles C12N2710/14061Methods of inactivation or attenuation C12N2710/14062by genetic engineering C12N2710/14063by chemical treatment C12N2710/14064by serial passage C12N2710/14071Demonstrated in vivo effect C12N2710/14088for redistribution C12N2710/14111Nucleopolyhedrovirus, e.g. autographa californica nucleopolyhedrovirus C12N2710/14121Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2710/14122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2710/14123Virus like particles [VLP] C12N2710/14131Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2710/14132Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2710/14133Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory C12N2710/14134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein C12N2710/14141Use of virus, viral particle or viral elements as a vector C12N2710/14142virus or viral particle as vehicle, e.g. encapsulating small organic molecule C12N2710/14143viral genome or elements thereof as genetic vector C12N2710/14144Chimeric viral vector comprising heterologous viral elements for production of another viral vector C12N2710/14145Special targeting system for viral vectors C12N2710/14151Methods of production or purification of viral material C12N2710/14152relating to complementing cells and packaging systems for producing virus or viral particles C12N2710/14161Methods of inactivation or attenuation C12N2710/14162by genetic engineering C12N2710/14163by chemical treatment C12N2710/14164by serial passage C12N2710/14171Demonstrated in vivo effect C12N2710/14188For redistribution C12N2710/16011Herpesviridae C12N2710/16021Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2710/16022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2710/16023Virus like particles [VLP] C12N2710/16031Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2710/16032Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2710/16033Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory C12N2710/16034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein C12N2710/16041Use of virus, viral particle or viral elements as a vector C12N2710/16042virus or viral particle as vehicle, e.g. encapsulating small organic molecule C12N2710/16043viral genome or elements thereof as genetic vector C12N2710/16044Chimeric viral vector comprising heterologous viral elements for production of another viral vector C12N2710/16045Special targeting system for viral vectors C12N2710/16051Methods of production or purification of viral material C12N2710/16052relating to complementing cells and packaging systems for producing virus or viral particles C12N2710/16061Methods of inactivation or attenuation C12N2710/16062by genetic engineering C12N2710/16063by chemical treatment C12N2710/16064by serial passage C12N2710/16071Demonstrated in vivo effect C12N2710/16088for redistribution C12N2710/16111Cytomegalovirus, e.g. human herpesvirus 5 C12N2710/16121Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2710/16122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2710/16123Virus like particles [VLP] C12N2710/16131Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2710/16132Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2710/16133Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory C12N2710/16134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein C12N2710/16141Use of virus, viral particle or viral elements as a vector C12N2710/16142virus or viral particle as vehicle, e.g. encapsulating small organic molecule C12N2710/16143viral genome or elements thereof as genetic vector C12N2710/16144Chimeric viral vector comprising heterologous viral elements for production of another viral vector C12N2710/16145Special targeting system for viral vectors C12N2710/16151Methods of production or purification of viral material C12N2710/16152relating to complementing cells and packaging systems for producing virus or viral particles C12N2710/16161Methods of inactivation or attenuation C12N2710/16162by genetic engineering C12N2710/16163by chemical treatment C12N2710/16164by serial passage C12N2710/16171Demonstrated in vivo effect C12N2710/16188for redistribution C12N2710/16211Lymphocryptovirus, e.g. human herpesvirus 4, Epstein-Barr Virus C12N2710/16221Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2710/16222New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2710/16223Virus like particles [VLP] C12N2710/16231Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2710/16232Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2710/16233Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory C12N2710/16234Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein C12N2710/16241Use of virus, viral particle or viral elements as a vector C12N2710/16242virus or viral particle as vehicle, e.g. encapsulating small organic molecule C12N2710/16243viral genome or elements thereof as genetic vector C12N2710/16244Chimeric viral vector comprising heterologous viral elements for production of another viral vector C12N2710/16245Special targeting system for viral vectors C12N2710/16251Methods of production or purification of viral material C12N2710/16252relating to complementing cells and packaging systems for producing virus or viral particles C12N2710/16261Methods of inactivation or attenuation C12N2710/16262by genetic engineering C12N2710/16263by chemical treatment C12N2710/16264by serial passage C12N2710/16271Demonstrated in vivo effect C12N2710/16288for redistribution C12N2710/16311Mardivirus, e.g. Gallid herpesvirus 2, Marek-like viruses, turkey HV C12N2710/16321Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2710/16322New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2710/16323Virus like particles [VLP] C12N2710/16331Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2710/16332Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2710/16333Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory C12N2710/16334Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein C12N2710/16341Use of virus, viral particle or viral elements as a vector C12N2710/16342virus or viral particle as vehicle, e.g. encapsulating small organic molecule C12N2710/16343viral genome or elements thereof as genetic vector C12N2710/16344Chimeric viral vector comprising heterologous viral elements for production of another viral vector C12N2710/16345Special targeting system for viral vectors C12N2710/16351Methods of production or purification of viral material C12N2710/16352relating to complementin g cells and packaging systems for producing virus or viral particles C12N2710/16361Methods of inactivation or attenuation C12N2710/16362by genetic engineering C12N2710/16363by chemical treatment C12N2710/16364by serial passage C12N2710/16371Demonstrated in vivo effect C12N2710/16388for redistribution C12N2710/16411Rhadinovirus, e.g. human herpesvirus 8 C12N2710/16421Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2710/16422New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2710/16423Virus like particles [VLP] C12N2710/16431Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2710/16432Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2710/16433Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory C12N2710/16434Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein C12N2710/16441Use of virus, viral particle or viral elements as a vector C12N2710/16442virus or viral particle as vehicle, e.g. encapsulating small organic molecule C12N2710/16443viral genome or elements thereof as genetic vector C12N2710/16444Chimeric viral vector comprising heterologous viral elements for production of another viral vector C12N2710/16445Special targeting system for viral vectors C12N2710/16451Methods of production or purification of viral material C12N2710/16452relating to complementing cells and packaging systems for producing virus or viral particles C12N2710/16461Methods of inactivation or attenuation C12N2710/16462by genetic engineering C12N2710/16463by chemical treatment C12N2710/16464by serial passage C12N2710/16471Demonstrated in vivo effect C12N2710/16488for redistribution C12N2710/16511Roseolovirus, e.g. human herpesvirus 6, 7 C12N2710/16521Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2710/16522New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2710/16523Virus like particles [VLP] C12N2710/16531Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2710/16532Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2710/16533Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory C12N2710/16534Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral C12N2710/16541Use of virus, viral particle or viral elements as a vector C12N2710/16542virus or viral particle as vehicle, e.g. encapsulating small organic molecule C12N2710/16543viral genome or elements thereof as genetic vector C12N2710/16544Chimeric viral vector comprising heterologous viral elements for production of another viral vector C12N2710/16545Special targeting system for viral vectors C12N2710/16551Methods of production or purification of viral material C12N2710/16552relating to complementing cells and packaging systems for producing virus or viral particles C12N2710/16561Methods of inactivation or attenuation C12N2710/16562by genetic engineering C12N2710/16563by chemical treatment C12N2710/16564by serial passage C12N2710/16571Demonstrated in vivo effect C12N2710/16588for redistribution C12N2710/16611Simplexvirus, e.g. human herpesvirus 1, 2 C12N2710/16621Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2710/16622New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2710/16623Virus like particles [VLP] C12N2710/16631Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2710/16632Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2710/16633Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory C12N2710/16634Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein C12N2710/16641Use of virus, viral particle or viral elements as a vector C12N2710/16642virus or viral particle as vehicle, e.g. encapsulating small organic molecule C12N2710/16643viral genome or elements thereof as genetic vector C12N2710/16644Chimeric viral vector comprising heterologous viral elements for production of another viral vector C12N2710/16645Special targeting system for viral vectors C12N2710/16651Methods of production or purification of viral material C12N2710/16652relating to complementing cells and packaging systems for producing virus or viral particles C12N2710/16661Methods of inactivation or attenuation C12N2710/16662by genetic engineering C12N2710/16663by chemical treatment C12N2710/16664by serial passage C12N2710/16671Demonstrated in vivo effect C12N2710/16688for redistribution C12N2710/16711Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies C12N2710/16721Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2710/16722New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2710/16723Virus like particles [VLP] C12N2710/16731Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2710/16732Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2710/16733Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory C12N2710/16734Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein C12N2710/16741Use of virus, viral particle or viral elements as a vector C12N2710/16742virus or viral particle as vehicle, e.g. encapsulating small organic molecule C12N2710/16743viral genome or elements thereof as genetic vector C12N2710/16744Chimeric viral vector comprising heterologous viral elements for production of another viral vector C12N2710/16745Special targeting system for viral vectors C12N2710/16751Methods of production or purification of viral material C12N2710/16752relating to complementing cells and packaging systems for producing virus or viral particles C12N2710/16761Methods of inactivation or attenuation C12N2710/16762by genetic engineering C12N2710/16763by chemical treatment C12N2710/16764by serial passage C12N2710/16771Demonstrated in vivo effect C12N2710/16788for redistribution C12N2710/18011Nimaviridae C12N2710/18021Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2710/18022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2710/18023Virus like particles [VLP] C12N2710/18031Uses of virus other than therapeutic or vaccine, e.g. 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genetic engineering C12N2710/18063by chemical treatment C12N2710/18064by serial passage C12N2710/18071Demonstrated in vivo effect C12N2710/18088for redistribution C12N2710/20011Papillomaviridae C12N2710/20021Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2710/20022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2710/20023Virus like particles [VLP] C12N2710/20031Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2710/20032Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2710/20033Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory C12N2710/20034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein C12N2710/20041Use of virus, viral particle or viral elements as a vector C12N2710/20042virus or viral particle as vehicle, e.g. encapsulating small organic molecule C12N2710/20043viral genome or elements thereof as genetic vector C12N2710/20044Chimeric viral vector comprising heterologous viral elements for production of another viral vector C12N2710/20045Special targeting system for viral vectors C12N2710/20051Methods of production or purification of viral material C12N2710/20052relating to complementing cells and packaging systems for producing virus or viral particles C12N2710/20061Methods of inactivation or attenuation C12N2710/20062by genetic engineering C12N2710/20063by chemical treatment C12N2710/20064by serial passage C12N2710/20071Demonstrated in vivo effect C12N2710/20088for redistribution C12N2710/22011Polyomaviridae, e.g. polyoma, SV40, JC C12N2710/22021Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2710/22022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2710/22023Virus like particles [VLP] C12N2710/22031Uses of virus 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inactivation or attenuation C12N2710/22062by genetic engineering C12N2710/22063by chemical treatment C12N2710/22064by serial passage C12N2710/22071Demonstrated in vivo effect C12N2710/22088for redistribution C12N2710/24011Poxviridae C12N2710/24021Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2710/24022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2710/24023Virus like particles [VLP] C12N2710/24031Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2710/24032Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2710/24033Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory C12N2710/24034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein C12N2710/24041Use of virus, viral particle or viral elements as a vector C12N2710/24042virus or viral particle as vehicle, e.g. encapsulating small organic molecule C12N2710/24043viral genome or elements thereof as genetic vector C12N2710/24044Chimeric viral vector comprising heterologous viral elements for production of another viral vector C12N2710/24045Special targeting system for viral vectors C12N2710/24051Methods of production or purification of viral material C12N2710/24052relating to complementing cells and packaging systems for producing virus or viral particles C12N2710/24061Methods of inactivation or attenuation C12N2710/24062by genetic engineering C12N2710/24063by chemical treatment C12N2710/24064by serial passage C12N2710/24071Demonstrated in vivo effect C12N2710/24088for redistribution C12N2710/24111Orthopoxvirus, e.g. vaccinia virus, variola C12N2710/24121Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2710/24122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2710/24123Virus like 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particles C12N2710/24161Methods of inactivation or attenuation C12N2710/24162by genetic engineering C12N2710/24163by chemical treatment C12N2710/24164by serial passage C12N2710/24171Demonstrated in vivo effect C12N2710/24188for redistribution C12N2710/24211Parapoxvirus, e.g. Orf virus C12N2710/24221Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2710/24222New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2710/24223Virus like particles [VLP] C12N2710/24231Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2710/24232Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2710/24233Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory C12N2710/24234Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein C12N2710/24241Use of virus, viral particle or viral elements as a vector C12N2710/24242virus or viral particle as vehicle, e.g. encapsulating small organic molecule C12N2710/24243viral genome or elements thereof as genetic vector C12N2710/24244Chimeric viral vector comprising heterologous viral elements for production of another viral vector C12N2710/24245Special targeting system for viral vectors C12N2710/24251Methods of production or purification of viral material C12N2710/24252relating to complementing cells and packaging systems for producing virus or viral particles C12N2710/24261Methods of inactivation or attenuation C12N2710/24262by genetic engineering C12N2710/24263by chemical treatment C12N2710/24264by serial passage C12N2710/24271Demonstrated in vivo effect C12N2710/24288for redistribution C12N2720/00dsRNA viruses C12N2720/00011Details C12N2720/00021Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2720/00022New viral proteins or individual genes, new structural or functional aspects of known 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packaging systems for producing virus or viral particles C12N2720/00061Methods of inactivation or attenuation C12N2720/00062by genetic engineering C12N2720/00063by chemical treatment C12N2720/00064by serial passage C12N2720/00071Demonstrated in vivo effect C12N2720/00088for redistribution C12N2720/10011Birnaviridae C12N2720/10021Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2720/10022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2720/10023Virus like particles [VLP] C12N2720/10031Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2720/10032Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2720/10033Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory C12N2720/10034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein C12N2720/10041Use of virus, viral particle or viral elements as a vector C12N2720/10042virus or viral particle as vehicle, e.g. encapsulating small organic molecule C12N2720/10043viral genome or elements thereof as genetic vector C12N2720/10044Chimeric viral vector comprising heterologous viral elements for production of another viral vector C12N2720/10045Special targeting system for viral vectors C12N2720/10051Methods of production or purification of viral material C12N2720/10052relating to complementing cells and packaging systems for producing virus or viral particles C12N2720/10061Methods of inactivation or attenuation C12N2720/10062by genetic engineering C12N2720/10063by chemical treatment C12N2720/10064by serial passage C12N2720/10071Demonstrated in vivo effect C12N2720/10088for redistribution C12N2720/12011Reoviridae C12N2720/12021Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2720/12022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2720/12023Virus like particles [VLP] C12N2720/12031Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2720/12032Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2720/12033Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory C12N2720/12034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein C12N2720/12041Use of virus, viral particle or viral elements as a vector C12N2720/12042virus or viral particle as vehicle, e.g. encapsulating small organic molecule C12N2720/12043viral genome or elements thereof as genetic vector C12N2720/12044Chimeric viral vector comprising heterologous viral elements for production of another viral vector C12N2720/12045Special targeting system for viral vectors C12N2720/12051Methods of production or purification of viral material C12N2720/12052relating to complementing cells and packaging systems for producing virus or viral particles C12N2720/12061Methods of inactivation or attenuation C12N2720/12062by genetic engineering C12N2720/12063by chemical treatment C12N2720/12064by serial passage C12N2720/12071Demonstrated in vivo effect C12N2720/12088for redistribution C12N2720/12111Orbivirus, e.g. bluetongue virus C12N2720/12121Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2720/12122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2720/12123Virus like particles [VLP] C12N2720/12131Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2720/12132Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2720/12133Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory C12N2720/12134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein C12N2720/12141Use of virus, viral particle or viral elements as a vector C12N2720/12142virus or viral particle as vehicle, e.g. encapsulating small organic molecule C12N2720/12143viral genome or elements thereof as genetic vector C12N2720/12144Chimeric viral vector comprising heterologous viral elements for production of another viral vector C12N2720/12145Special targeting system for viral vectors C12N2720/12151Methods of production or purification of viral material C12N2720/12152relating to complementing cells and packaging systems for producing virus or viral particles C12N2720/12161Methods of inactivation or attenuation C12N2720/12162by genetic engineering C12N2720/12163by chemical treatment C12N2720/12164by serial passage C12N2720/12171Demonstrated in vivo effect C12N2720/12188for redistribution C12N2720/12211Orthoreovirus, e.g. mammalian orthoreovirus C12N2720/12221Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2720/12222New viral proteins 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of viral material C12N2720/12252relating to complementing cells and packaging systems for producing virus or viral particles C12N2720/12261Methods of inactivation or attenuation C12N2720/12262by genetic engineering C12N2720/12263by chemical treatment C12N2720/12264by serial passage C12N2720/12271Demonstrated in vivo effect C12N2720/12288for redistribution C12N2720/12311Rotavirus, e.g. rotavirus A C12N2720/12321Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2720/12322New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2720/12323Virus like particles [VLP] C12N2720/12331Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2720/12332Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2720/12333Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory C12N2720/12334Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein C12N2720/12341Use of virus, viral particle or viral elements as a vector C12N2720/12342virus or viral particle as vehicle, e.g. encapsulating small organic molecule C12N2720/12343viral genome or elements thereof as genetic vector C12N2720/12344Chimeric viral vector comprising heterologous viral elements for production of another viral vector C12N2720/12345Special targeting system for viral vectors C12N2720/12351Methods of production or purification of viral material C12N2720/12352relating to complementing cells and packaging systems for producing virus or viral particles C12N2720/12361Methods of inactivation or attenuation C12N2720/12362by genetic engineering C12N2720/12363by chemical treatment C12N2720/12364by serial passage C12N2720/12371Demonstrated in vivo effect C12N2720/12388for redistribution C12N2730/00Reverse transcribing DNA viruses C12N2730/00011Details C12N2730/00021Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2730/00022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2730/00023Virus like particles [VLP] C12N2730/00031Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2730/00032Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2730/00033Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory C12N2730/00034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein C12N2730/00041Use of virus, viral particle or viral elements as a vector C12N2730/00042virus or viral particle as vehicle, e.g. encapsulating small organic molecule C12N2730/00043viral genome or elements thereof as genetic vector C12N2730/00044Chimeric viral vector comprising heterologous viral elements for production of another viral vector C12N2730/00045Special targeting system for viral vectors C12N2730/00051Methods of production or purification of viral material C12N2730/00052relating to complementing cells and packaging systems for producing virus or viral particles C12N2730/00061Methods of inactivation or attenuation C12N2730/00062by genetic engineering C12N2730/00063by chemical treatment C12N2730/00064by serial passage C12N2730/00071Demonstrated in vivo effect C12N2730/00088for redistribution C12N2730/10011Hepadnaviridae C12N2730/10021Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2730/10022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2730/10023Virus like particles [VLP] C12N2730/10031Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2730/10032Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2730/10033Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or 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serial passage C12N2740/11071Demonstrated in vivo effect C12N2740/11088for redistribution C12N2740/12011Betaretrovirus, e.g. mouse mammary tumour virus C12N2740/12021Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2740/12022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2740/12023Virus like particles [VLP] C12N2740/12031Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2740/12032Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2740/12033Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory C12N2740/12034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein C12N2740/12041Use of virus, viral particle or viral elements as a vector C12N2740/12042virus or viral particle as vehicle, e.g. encapsulating small organic molecule C12N2740/12043viral genome or elements thereof as genetic vector C12N2740/12044Chimeric viral vector comprising heterologous viral elements for production of another viral vector C12N2740/12045Special targeting system for viral vectors C12N2740/12051Methods of production or purification of viral material C12N2740/12052relating to complementing cells and packaging systems for producing virus or viral particles C12N2740/12061Methods of inactivation or attenuation C12N2740/12062by genetic engineering C12N2740/12063by chemical treatment C12N2740/12064by serial passage C12N2740/12071Demonstrated in vivo effect C12N2740/12088for redistribution C12N2740/13011Gammaretrovirus, e.g. murine leukeamia virus C12N2740/13021Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2740/13022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2740/13023Virus like particles [VLP] C12N2740/13031Uses of virus other than 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attenuation C12N2740/13062by genetic engineering C12N2740/13063by chemical treatment C12N2740/13064by serial passage C12N2740/13071Demonstrated in vivo effect C12N2740/13088for redistribution C12N2740/14011Deltaretrovirus, e.g. bovine leukeamia virus C12N2740/14021Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2740/14022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2740/14023Virus like particles [VLP] C12N2740/14031Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2740/14032Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2740/14033Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory C12N2740/14034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein C12N2740/14041Use of virus, viral particle or viral elements as a vector 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producing virus or viral particles C12N2740/15061Methods of inactivation or attenuation C12N2740/15062by genetic engineering C12N2740/15063by chemical treatment C12N2740/15064by serial passage C12N2740/15071Demonstrated in vivo effect C12N2740/15088for redistribution C12N2740/16011Human Immunodeficiency Virus, HIV C12N2740/16021Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2740/16022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2740/16023Virus like particles [VLP] C12N2740/16031Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2740/16032Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2740/16033Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory C12N2740/16034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein C12N2740/16041Use of virus, viral particle or viral elements as a vector C12N2740/16042virus or viral particle as vehicle, e.g. encapsulating small organic molecule C12N2740/16043viral genome or elements thereof as genetic vector C12N2740/16044Chimeric viral vector comprising heterologous viral elements for production of another viral vector C12N2740/16045Special targeting system for viral vectors C12N2740/16051Methods of production or purification of viral material C12N2740/16052relating to complementing cells and packaging systems for producing virus or viral particles C12N2740/16061Methods of inactivation or attenuation C12N2740/16062by genetic engineering C12N2740/16063by chemical treatment C12N2740/16064by serial passage C12N2740/16071Demonstrated in vivo effect C12N2740/16088for redistribution C12N2740/16111concerning HIV env C12N2740/16122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2740/16134Use of virus or viral component as 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apoptosis inducing or anti-inflammatory C12N2750/12034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein C12N2750/12041Use of virus, viral particle or viral elements as a vector C12N2750/12042virus or viral particle as vehicle, e.g. encapsulating small organic molecule C12N2750/12043viral genome or elements thereof as genetic vector C12N2750/12044Chimeric viral vector comprising heterologous viral elements for production of another viral vector C12N2750/12045Special targeting system for viral vectors C12N2750/12051Methods of production or purification of viral material C12N2750/12052relating to complementing cells and packaging systems for producing virus or viral particles C12N2750/12061Methods of inactivation or attenuation C12N2750/12062by genetic engineering C12N2750/12063by chemical treatment C12N2750/12064by serial passage C12N2750/12071Demonstrated in vivo effect C12N2750/12088for redistribution C12N2750/14011Parvoviridae 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viral vector C12N2750/14045Special targeting system for viral vectors C12N2750/14051Methods of production or purification of viral material C12N2750/14052relating to complementing cells and packaging systems for producing virus or viral particles C12N2750/14061Methods of inactivation or attenuation C12N2750/14062by genetic engineering C12N2750/14063by chemical treatment C12N2750/14064by serial passage C12N2750/14071Demonstrated in vivo effect C12N2750/14088for redistribution C12N2750/14111Dependovirus, e.g. adenoassociated viruses C12N2750/14121Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2750/14122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2750/14123Virus like particles [VLP] C12N2750/14131Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2750/14132Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2750/14133Use of viral protein as 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heterologous viral elements for production of another viral vector C12N2750/14245Special targeting system for viral vectors C12N2750/14251Methods of production or purification of viral material C12N2750/14252relating to complementing cells and packaging systems for producing virus or viral particles C12N2750/14261Methods of inactivation or attenuation C12N2750/14262by genetic engineering C12N2750/14263by chemical treatment C12N2750/14264by serial passage C12N2750/14271Demonstrated in vivo effect C12N2750/14288for redistribution C12N2750/14311Parvovirus, e.g. minute virus of mice C12N2750/14321Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2750/14322New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2750/14323Virus like particles [VLP] C12N2750/14331Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2750/14332Use of virus as therapeutic agent, other than vaccine, e.g. as 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C12N2750/14371Demonstrated in vivo effect C12N2750/14388for redistribution C12N2760/00ssRNA viruses negative-sense C12N2760/00011Details C12N2760/00021Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2760/00022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2760/00023Virus like particles [VLP] C12N2760/00031Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2760/00032Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2760/00033Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory C12N2760/00034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein C12N2760/00041Use of virus, viral particle or viral elements as a vector C12N2760/00042virus or viral particle as vehicle, e.g. encapsulating small organic molecule C12N2760/00043viral genome or elements thereof as genetic vector C12N2760/00044Chimeric viral vector comprising heterologous viral elements for production of another viral vector C12N2760/00045Special targeting system for viral vectors C12N2760/00051Methods of production or purification of viral material C12N2760/00052relating to complementing cells and packaging systems for producing virus or viral particles C12N2760/00061Methods of inactivation or attenuation C12N2760/00062by genetic engineering C12N2760/00063by chemical treatment C12N2760/00064by serial passage C12N2760/00071Demonstrated in vivo effect C12N2760/00088for redistribution C12N2760/10011Arenaviridae C12N2760/10021Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2760/10022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2760/10023Virus like particles [VLP] C12N2760/10031Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2760/10032Use of virus 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treatment C12N2760/10064by serial passage C12N2760/10071Demonstrated in vivo effect C12N2760/10088for redistribution C12N2760/10111Deltavirus, e.g. hepatitis delta virus C12N2760/10121Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2760/10122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2760/10123Virus like particles [VLP] C12N2760/10131Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2760/10132Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2760/10133Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory C12N2760/10134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein C12N2760/10141Use of virus, viral particle or viral elements as a vector C12N2760/10142virus or viral particle as vehicle, e.g. encapsulating small organic molecule C12N2760/10143viral genome or elements thereof as genetic vector C12N2760/10144Chimeric viral vector comprising heterologous viral elements for production of another viral vector C12N2760/10145Special targeting system for viral vectors C12N2760/10151Methods of production or purification of viral material C12N2760/10152relating to complementing cells and packaging systems for producing virus or viral particles C12N2760/10161Methods of inactivation or attenuation C12N2760/10162by genetic engineering C12N2760/10163by chemical treatment C12N2760/10164by serial passage C12N2760/10171Demonstrated in vivo effect C12N2760/10188for redistribution C12N2760/12011Bunyaviridae C12N2760/12021Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2760/12022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2760/12023Virus like particles [VLP] C12N2760/12031Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2760/12032Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2760/12033Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory C12N2760/12034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein C12N2760/12041Use of virus, viral particle or viral elements as a vector C12N2760/12042virus or viral particle as vehicle, e.g. encapsulating small organic molecule C12N2760/12043viral genome or elements thereof as genetic vector C12N2760/12044Chimeric viral vector comprising heterologous viral elements for production of another viral vector C12N2760/12045Special targeting system for viral vectors C12N2760/12051Methods of production or purification of viral material C12N2760/12052relating to complementing cells and packaging systems for producing virus or viral particles C12N2760/12061Methods of inactivation or attenuation C12N2760/12062by genetic engineering C12N2760/12063by chemical treatment C12N2760/12064by serial passage C12N2760/12071Demonstrated in vivo effect C12N2760/12088for redistribution C12N2760/12111Hantavirus, e.g. Hantaan virus C12N2760/12121Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2760/12122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2760/12123Virus like particles [VLP] C12N2760/12131Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2760/12132Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2760/12133Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory C12N2760/12134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein C12N2760/12141Use of virus, viral particle or viral elements as a vector C12N2760/12142virus or viral particle as vehicle, e.g. encapsulating small organic molecule C12N2760/12143viral genome or elements thereof as genetic vector C12N2760/12144Chimeric viral vector comprising heterologous viral elements for production of another viral vector C12N2760/12145Special targeting system for viral vectors C12N2760/12151Methods of production or purification of viral material C12N2760/12152relating to complementing cells and packaging systems for producing virus or viral particles C12N2760/12161Methods of inactivation or attenuation C12N2760/12162by genetic engineering C12N2760/12163by chemical treatment C12N2760/12164by serial passage C12N2760/12171Demonstrated in vivo effect C12N2760/12188for redistribution C12N2760/12211Phlebovirus, e.g. Rift Valley fever virus C12N2760/12221Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2760/12222New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2760/12223Virus like particles [VLP] C12N2760/12231Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2760/12232Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2760/12233Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory C12N2760/12234Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein C12N2760/12241Use of virus, viral particle or viral elements as a vector C12N2760/12242virus or viral particle as vehicle, e.g. encapsulating small organic molecule C12N2760/12243viral genome or elements thereof as genetic vector C12N2760/12244Chimeric viral vector comprising heterologous viral elements for production of another viral vector C12N2760/12245Special targeting system for viral vectors C12N2760/12251Methods of production or purification of viral material C12N2760/12252relating to complementing cells and packaging systems for producing virus or viral particles C12N2760/12261Methods of inactivation or attenuation C12N2760/12262by genetic engineering C12N2760/12263by chemical treatment C12N2760/12264by serial passage C12N2760/12271Demonstrated in vivo effect C12N2760/12288for redistribution C12N2760/14011Filoviridae C12N2760/14021Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2760/14022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2760/14023Virus like particles [VLP] C12N2760/14031Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2760/14032Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2760/14033Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory C12N2760/14034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein C12N2760/14041Use of virus, viral particle or viral elements as a vector C12N2760/14042virus or viral particle as vehicle, e.g. encapsulating small organic molecule C12N2760/14043viral genome or elements thereof as genetic vector C12N2760/14044Chimeric viral vector comprising heterologous viral elements for production of another viral vector C12N2760/14045Special targeting system for viral vectors C12N2760/14051Methods of production or purification of viral material C12N2760/14052relating to complementing cells and packaging systems for producing virus or viral particles C12N2760/14061Methods of inactivation or attenuation C12N2760/14062by genetic engineering C12N2760/14063by chemical treatment C12N2760/14064by serial passage C12N2760/14071Demonstrated in vivo effect C12N2760/14088for redistribution C12N2760/14111Ebolavirus, e.g. Zaire ebolavirus C12N2760/14121Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2760/14122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2760/14123Virus like particles [VLP] C12N2760/14131Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2760/14132Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2760/14133Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory C12N2760/14134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein C12N2760/14141Use of virus, viral particle or viral elements as a vector C12N2760/14142virus or viral particle as vehicle, e.g. encapsulating small organic molecule C12N2760/14143viral genome or elements thereof as genetic vector C12N2760/14144Chimeric viral vector comprising heterologous viral elements for production of another viral vector C12N2760/14145Special targeting system for viral vectors C12N2760/14151Methods of production or purification of viral material C12N2760/14152relating to complementing cells and packaging systems for producing virus or viral particles C12N2760/14161Methods of inactivation or attenuation C12N2760/14162by genetic engineering C12N2760/14163by chemical treatment C12N2760/14164by serial passage C12N2760/14171Demonstrated in vivo effect C12N2760/14188for redistribution C12N2760/14211Marburgvirus, e.g. lake Victoria marburgvirus C12N2760/14221Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2760/14222New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2760/14223Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2760/14231Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2760/14232Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2760/14233Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory C12N2760/14234Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein C12N2760/14241Use of virus, viral particle or viral elements as a vector C12N2760/14242virus or viral particle as vehicle, e.g. encapsulating small organic molecule C12N2760/14243viral genome or elements thereof as genetic vector C12N2760/14244Chimeric viral vector comprising heterologous viral elements for production of another viral vector C12N2760/14245Special targeting system for viral vectors C12N2760/14251Methods of production or purification of viral material C12N2760/14252relating to complementing cells and packaging systems for producing virus or viral particles C12N2760/14261Methods of inactivation or attenuation C12N2760/14262by genetic engineering C12N2760/14263by chemical treatment C12N2760/14264by serial passage C12N2760/14271Demonstrated in vivo effect C12N2760/14288for redistribution C12N2760/16011Orthomyxoviridae C12N2760/16021Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2760/16022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2760/16023Virus like particles [VLP] C12N2760/16031Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2760/16032Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2760/16033Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory C12N2760/16034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein C12N2760/16041Use of virus, viral particle or viral elements as a vector C12N2760/16042virus or viral particle as vehicle, e.g. encapsulating small organic molecule C12N2760/16043viral genome or elements thereof as genetic vector C12N2760/16044Chimeric viral vector comprising heterologous viral elements for production of another viral vector C12N2760/16045Special targeting system for viral vectors C12N2760/16051Methods of production or purification of viral material C12N2760/16052relating to complementing cells and packaging systems for producing virus or viral particles C12N2760/16061Methods of inactivation or attenuation C12N2760/16062by genetic engineering C12N2760/16063by chemical treatment C12N2760/16064by serial passage C12N2760/16071Demonstrated in vivo effect C12N2760/16088for redistribution C12N2760/16111Influenzavirus A, i.e. influenza A virus C12N2760/16121Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2760/16122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2760/16123Virus like particles [VLP] C12N2760/16131Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2760/16132Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2760/16133Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory C12N2760/16134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein C12N2760/16141Use of virus, viral particle or viral elements as a vector C12N2760/16142virus or viral particle as vehicle, e.g. encapsulating small organic molecule C12N2760/16143viral genome or elements thereof as genetic vector C12N2760/16144Chimeric viral vector comprising heterologous viral elements for production of another viral vector C12N2760/16145Special targeting system for viral vectors C12N2760/16151Methods of production or purification of viral material C12N2760/16152relating to complementing cells and packaging systems for producing virus or viral particles C12N2760/16161Methods of inactivation or attenuation C12N2760/16162by genetic engineering C12N2760/16163by chemical treatment C12N2760/16164by serial passage C12N2760/16171Demonstrated in vivo effect C12N2760/16188for redistribution C12N2760/16211Influenzavirus B, i.e. influenza B virus C12N2760/16221Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2760/16222New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2760/16223Virus like particles [VLP] C12N2760/16231Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2760/16232Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2760/16233Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory C12N2760/16234Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein C12N2760/16241Use of virus, viral particle or viral elements as a vector C12N2760/16242virus or viral particle as vehicle, e.g. encapsulating small organic molecule C12N2760/16243viral genome or elements thereof as genetic vector C12N2760/16244Chimeric viral vector comprising heterologous viral elements for production of another viral vector C12N2760/16245Special targeting system for viral vectors C12N2760/16251Methods of production or purification of viral material C12N2760/16252relating to complementing cells and packaging systems for producing virus or viral particles C12N2760/16261Methods of inactivation or attenuation C12N2760/16262by genetic engineering C12N2760/16263by chemical treatment C12N2760/16264by serial passage C12N2760/16271Demonstrated in vivo effect C12N2760/16288for redistribution C12N2760/16311Influenzavirus C, i.e. influenza C virus C12N2760/16321Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2760/16322New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2760/16323Virus like particles [VLP] C12N2760/16331Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2760/16332Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2760/16333Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory C12N2760/16334Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein C12N2760/16341Use of virus, viral particle or viral elements as a vector C12N2760/16342virus or viral particle as vehicle, e.g. encapsulating small organic molecule C12N2760/16343viral genome or elements thereof as genetic vector C12N2760/16344Chimeric viral vector comprising heterologous viral elements for production of another viral vector C12N2760/16345Special targeting system for viral vectors C12N2760/16351Methods of production or purification of viral material C12N2760/16352relating to complementing cells and packaging systems for producing virus or viral particles C12N2760/16361Methods of inactivation or attenuation C12N2760/16362by genetic engineering C12N2760/16363by chemical treatment C12N2760/16364by serial passage C12N2760/16371Demonstrated in vivo effect C12N2760/16388for redistribution C12N2760/18011Paramyxoviridae C12N2760/18021Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2760/18022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2760/18023Virus like particles [VLP] C12N2760/18031Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2760/18032Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2760/18033Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory C12N2760/18034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein C12N2760/18041Use of virus, viral particle or viral elements as a vector C12N2760/18042virus or viral particle as vehicle, e.g. encapsulating small organic molecule C12N2760/18043viral genome or elements thereof as genetic vector C12N2760/18044Chimeric viral vector comprising heterologous viral elements for production of another viral vector C12N2760/18045Special targeting system for viral vectors C12N2760/18051Methods of production or purification of viral material C12N2760/18052relating to complementing cells and packaging systems for producing virus or viral particles C12N2760/18061Methods of inactivation or attenuation C12N2760/18062by genetic engineering C12N2760/18063by chemical treatment C12N2760/18064by serial passage C12N2760/18071Demonstrated in vivo effect C12N2760/18088for redistribution C12N2760/18111Avulavirus, e.g. Newcastle disease virus C12N2760/18121Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2760/18122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2760/18123Virus like particles [VLP] C12N2760/18131Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2760/18132Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2760/18133Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory C12N2760/18134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein C12N2760/18141Use of virus, viral particle or viral elements as a vector C12N2760/18142virus or viral particle as vehicle, e.g. encapsulating small organic molecule C12N2760/18143viral genome or elements thereof as genetic vector C12N2760/18144Chimeric viral vector comprising heterologous viral elements for production of another viral vector C12N2760/18145Special targeting system for viral vectors C12N2760/18151Methods of production or purification of viral material C12N2760/18152relating to complementing cells and packaging systems for producing virus or viral particles C12N2760/18161Methods of inactivation or attenuation C12N2760/18162by genetic engineering C12N2760/18163by chemical treatment C12N2760/18164by serial passage C12N2760/18171Demonstrated in vivo effect C12N2760/18188for redistribution C12N2760/18211Henipavirus, e.g. hendra virus C12N2760/18221Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2760/18222New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2760/18223Virus like particles [VLP] C12N2760/18231Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2760/18232Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2760/18233Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory C12N2760/18234Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein C12N2760/18241Use of virus, viral particle or viral elements as a vector C12N2760/18242virus or viral particle as vehicle, e.g. encapsulating small organic molecule C12N2760/18243viral genome or elements thereof as genetic vector C12N2760/18244Chimeric viral vector comprising heterologous viral elements for production of another viral vector C12N2760/18245Special targeting system for viral vectors C12N2760/18251Methods of production or purification of viral material C12N2760/18252relating to complementing cells and packaging systems for producing virus or viral particles C12N2760/18261Methods of inactivation or attenuation C12N2760/18262by genetic engineering C12N2760/18263by chemical treatment C12N2760/18264by serial passage C12N2760/18271Demonstrated in vivo effect C12N2760/18288for redistribution C12N2760/18311Metapneumovirus, e.g. avian pneumovirus C12N2760/18321Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2760/18322New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2760/18323Virus like particles [VLP] C12N2760/18331Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2760/18332Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2760/18333Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory C12N2760/18334Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein C12N2760/18341Use of virus, viral particle or viral elements as a vector C12N2760/18342virus or viral particle as vehicle, e.g. encapsulating small organic molecule C12N2760/18343viral genome or elements thereof as genetic vector C12N2760/18344Chimeric viral vector comprising heterologous viral elements for production of another viral vector C12N2760/18345Special targeting system for viral vectors C12N2760/18351Methods of production or purification of viral material C12N2760/18352relating to complementing cells and packaging systems for producing virus or viral particles C12N2760/18361Methods of inactivation or attenuation C12N2760/18362by genetic engineering C12N2760/18363by chemical treatment C12N2760/18364by serial passage C12N2760/18371Demonstrated in vivo effect C12N2760/18388for redistribution C12N2760/18411Morbillivirus, e.g. Measles virus, canine distemper C12N2760/18421Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2760/18422New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2760/18423Virus like particles [VLP] C12N2760/18431Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2760/18432Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2760/18433Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory C12N2760/18434Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein C12N2760/18441Use of virus, viral particle or viral elements as a vector C12N2760/18442virus or viral particle as vehicle, e.g. encapsulating small organic molecule C12N2760/18443viral genome or elements thereof as genetic vector C12N2760/18444Chimeric viral vector comprising heterologous viral elements for production of another viral vector C12N2760/18445Special targeting system for viral vectors C12N2760/18451Methods of production or purification of viral material C12N2760/18452relating to complementing cells and packaging systems for producing virus or viral particles C12N2760/18461Methods of inactivation or attenuation C12N2760/18462by genetic engineering C12N2760/18463by chemical treatment C12N2760/18464by serial passage C12N2760/18471Demonstrated in vivo effect C12N2760/18488For redistribution C12N2760/18511Pneumovirus, e.g. human respiratory syncytial virus C12N2760/18521Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2760/18522New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2760/18523Virus like particles [VLP] C12N2760/18531Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2760/18532Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2760/18533Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory C12N2760/18534Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein C12N2760/18541Use of virus, viral particle or viral elements as a vector C12N2760/18542virus or viral particle as vehicle, e.g. encapsulating small organic molecule C12N2760/18543viral genome or elements thereof as genetic vector C12N2760/18544Chimeric viral vector comprising heterologous viral elements for production of another viral vector C12N2760/18545Special targeting system for viral vectors C12N2760/18551Methods of production or purification of viral material C12N2760/18552relating to complementing cells and packaging systems for producing virus or viral particles C12N2760/18561Methods of inactivation or attenuation C12N2760/18562by genetic engineering C12N2760/18563by chemical treatment C12N2760/18564by serial passage C12N2760/18571Demonstrated in vivo effect C12N2760/18588for redistribution C12N2760/18611Respirovirus, e.g. Bovine, human parainfluenza 1,3 C12N2760/18621Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2760/18622New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2760/18623Virus like particles [VLP] C12N2760/18631Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2760/18632Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2760/18633Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory C12N2760/18634Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein C12N2760/18641Use of virus, viral particle or viral elements as a vector C12N2760/18642virus or viral particle as vehicle, e.g. encapsulating small organic molecule C12N2760/18643viral genome or elements thereof as genetic vector C12N2760/18644Chimeric viral vector comprising heterologous viral elements for production of another viral vector C12N2760/18645Special targeting system for viral vectors C12N2760/18651Methods of production or purification of viral material C12N2760/18652relating to complementing cells and packaging systems for producing virus or viral particles C12N2760/18661Methods of inactivation or attenuation C12N2760/18662by genetic engineering C12N2760/18663by chemical treatment C12N2760/18664by serial passage C12N2760/18671Demonstrated in vivo effect C12N2760/18688for redistribution C12N2760/18711Rubulavirus, e.g. mumps virus, parainfluenza 2,4 C12N2760/18721Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2760/18722New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2760/18723Virus like particles [VLP] C12N2760/18731Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2760/18732Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2760/18733Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory C12N2760/18734Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein C12N2760/18741Use of virus, viral particle or viral elements as a vector C12N2760/18742virus or viral particle as vehicle, e.g. encapsulating small organic molecule C12N2760/18743viral genome or elements thereof as genetic vector C12N2760/18744Chimeric viral vector comprising heterologous viral elements for production of another viral vector C12N2760/18745Special targeting system for viral vectors C12N2760/18751Methods of production or purification of viral material C12N2760/18752relating to complementing cells and packaging systems for producing virus or viral particles C12N2760/18761Methods of inactivation or attenuation C12N2760/18762by genetic engineering C12N2760/18763by chemical treatment C12N2760/18764by serial passage C12N2760/18771Demonstrated in vivo effect C12N2760/18788for redistribution C12N2760/18811Sendai virus C12N2760/18821Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2760/18822New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2760/18823Virus like particles [VLP] C12N2760/18831Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2760/18832Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2760/18833Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory C12N2760/18834Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein C12N2760/18841Use of virus, viral particle or viral elements as a vector C12N2760/18842virus or viral particle as vehicle, e.g. encapsulating small organic molecule C12N2760/18843viral genome or elements thereof as genetic vector C12N2760/18845Special targeting system for viral vectors C12N2760/18851Methods of production or purification of viral material C12N2760/18852relating to complementing cells and packaging systems for producing virus or viral particles C12N2760/18861Methods of inactivation or attenuation C12N2760/18862by genetic engineering C12N2760/18863by chemical treatment C12N2760/18864by serial passage C12N2760/18871Demonstrated in vivo effect C12N2760/18888for redistribution C12N2760/20011Rhabdoviridae C12N2760/20021Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2760/20022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2760/20023Virus like particles [VLP] C12N2760/20031Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2760/20032Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2760/20033Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory C12N2760/20034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein C12N2760/20041Use of virus, viral particle or viral elements as a vector C12N2760/20042virus or viral particle as vehicle, e.g. encapsulating small organic molecule C12N2760/20043viral genome or elements thereof as genetic vector C12N2760/20044Chimeric viral vector comprising heterologous viral elements for production of another viral vector C12N2760/20045Special targeting system for viral vectors C12N2760/20051Methods of production or purification of viral material C12N2760/20052relating to complementing cells and packaging systems for producing virus or viral particles C12N2760/20061Methods of inactivation or attenuation C12N2760/20062by genetic engineering C12N2760/20063by chemical treatment C12N2760/20064by serial passage C12N2760/20071Demonstrated in vivo effect C12N2760/20088for redistribution C12N2760/20111Lyssavirus, e.g. rabies virus C12N2760/20121Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2760/20122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2760/20123Virus like particles [VLP] C12N2760/20131Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2760/20132Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2760/20133Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory C12N2760/20134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein C12N2760/20141Use of virus, viral particle or viral elements as a vector C12N2760/20142virus or viral particle as vehicle, e.g. encapsulating small organic molecule C12N2760/20143viral genome or elements thereof as genetic vector C12N2760/20144Chimeric viral vector comprising heterologous viral elements for production of another viral vector C12N2760/20145Special targeting system for viral vectors C12N2760/20151Methods of production or purification of viral material C12N2760/20152relating to complementing cells and packaging systems for producing virus or viral particles C12N2760/20161Methods of inactivation or attenuation C12N2760/20162by genetic engineering C12N2760/20163by chemical treatment C12N2760/20164by serial passage C12N2760/20171Demonstrated in vivo effect C12N2760/20188for redistribution C12N2760/20211Vesiculovirus, e.g. vesicular stomatitis Indiana virus C12N2760/20221Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2760/20222New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2760/20223Virus like particles [VLP] C12N2760/20231Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2760/20232Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2760/20233Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory C12N2760/20234Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein C12N2760/20241Use of virus, viral particle or viral elements as a vector C12N2760/20242virus or viral particle as vehicle, e.g. encapsulating small organic molecule C12N2760/20243viral genome or elements thereof as genetic vector C12N2760/20244Chimeric viral vector comprising heterologous viral elements for production of another viral vector C12N2760/20245Special targeting system for viral vectors C12N2760/20251Methods of production or purification of viral material C12N2760/20252relating to complementing cells and packaging systems for producing virus or viral particles C12N2760/20261Methods of inactivation or attenuation C12N2760/20262by genetic engineering C12N2760/20263by chemical treatment C12N2760/20264by serial passage C12N2760/20271Demonstrated in vivo effect C12N2760/20288for redistribution C12N2770/00ssRNA viruses positive-sense C12N2770/00011Details C12N2770/00021Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2770/00022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2770/00023Virus like particles [VLP] C12N2770/00031Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2770/00032Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2770/00033Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory C12N2770/00034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein C12N2770/00041Use of virus, viral particle or viral elements as a vector C12N2770/00042virus or viral particle as vehicle, e.g. encapsulating small organic molecule C12N2770/00043viral genome or elements thereof as genetic vector C12N2770/00044Chimeric viral vector comprising heterologous viral elements for production of another viral vector C12N2770/00045Special targeting system for viral vectors C12N2770/00051Methods of production or purification of viral material C12N2770/00052relating to complementing cells and packaging systems for producing virus or viral particles C12N2770/00061Methods of inactivation or attenuation C12N2770/00062by genetic engineering C12N2770/00063by chemical treatment C12N2770/00064by serial passage C12N2770/00071Demonstrated in vivo effect C12N2770/00088for redistribution C12N2770/10011Arteriviridae C12N2770/10021Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2770/10022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2770/10023Virus like particles [VLP] C12N2770/10031Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2770/10032Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2770/10033Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory C12N2770/10034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein C12N2770/10041Use of virus, viral particle or viral elements as a vector C12N2770/10042virus or viral particle as vehicle, e.g. encapsulating small organic molecule C12N2770/10043viral genome or elements thereof as genetic vector C12N2770/10044Chimeric viral vector comprising heterologous viral elements for production of another viral vector C12N2770/10045Special targeting system for viral vectors C12N2770/10051Methods of production or purification of viral material C12N2770/10052relating to complementing cells and packaging systems for producing virus or viral particles C12N2770/10061Methods of inactivation or attenuation C12N2770/10062by genetic engineering C12N2770/10063by chemical treatment C12N2770/10064by serial passage C12N2770/10071Demonstrated in vivo effect C12N2770/10088for redistribution C12N2770/12011Astroviridae C12N2770/12021Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2770/12022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2770/12023Virus like particles [VLP] C12N2770/12031Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2770/12032Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2770/12033Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory C12N2770/12034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein C12N2770/12041Use of virus, viral particle or viral elements as a vector C12N2770/12042virus or viral particle as vehicle, e.g. encapsulating small organic molecule C12N2770/12043viral genome or elements thereof as genetic vector C12N2770/12044Chimeric viral vector comprising heterologous viral elements for production of another viral vector C12N2770/12045Special targeting system for viral vectors C12N2770/12051Methods of production or purification of viral material C12N2770/12052relating to complementing cells and packaging systems for producing virus or viral particles C12N2770/12061Methods of inactivation or attenuation C12N2770/12062by genetic engineering C12N2770/12063by chemical treatment C12N2770/12064by serial passage C12N2770/12071Demonstrated in vivo effect C12N2770/12088for redistribution C12N2770/14011Bromoviridae C12N2770/14021Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2770/14022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2770/14023Virus like particles [VLP] C12N2770/14031Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2770/14032Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2770/14033Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory C12N2770/14034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein C12N2770/14041Use of virus, viral particle or viral elements as a vector C12N2770/14042virus or viral particle as vehicle, e.g. encapsulating small organic molecule C12N2770/14043viral genome or elements thereof as genetic vector C12N2770/14044Chimeric viral vector comprising heterologous viral elements for production of another viral vector C12N2770/14045Special targeting system for viral vectors C12N2770/14051Methods of production or purification of viral material C12N2770/14052relating to complementing cells and packaging systems for producing virus or viral particles C12N2770/14061Methods of inactivation or attenuation C12N2770/14062by genetic engineering C12N2770/14063by chemical treatment C12N2770/14064by serial passage C12N2770/14071Demonstrated in vivo effect C12N2770/14088for redistribution C12N2770/16011Caliciviridae C12N2770/16021Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2770/16022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2770/16023Virus like particles [VLP] C12N2770/16031Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2770/16032Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2770/16033Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory C12N2770/16034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein C12N2770/16041Use of virus, viral particle or viral elements as a vector C12N2770/16042virus or viral particle as vehicle, e.g. encapsulating small organic molecule C12N2770/16043viral genome or elements thereof as genetic vector C12N2770/16044Chimeric viral vector comprising heterologous viral elements for production of another viral vector C12N2770/16045Special targeting system for viral vectors C12N2770/16051Methods of production or purification of viral material C12N2770/16052relating to complementing cells and packaging systems for producing virus or viral particles C12N2770/16061Methods of inactivation or attenuation C12N2770/16062by genetic engineering C12N2770/16063by chemical treatment C12N2770/16064by serial passage C12N2770/16071Demonstrated in vivo effect C12N2770/16088for redistribution C12N2770/18011Comoviridae C12N2770/18021Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2770/18022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2770/18023Virus like particles [VLP] C12N2770/18031Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2770/18032Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2770/18033Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory C12N2770/18034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein C12N2770/18041Use of virus, viral particle or viral elements as a vector C12N2770/18042virus or viral particle as vehicle, e.g. encapsulating small organic molecule C12N2770/18043viral genome or elements thereof as genetic vector C12N2770/18044Chimeric viral vector comprising heterologous viral elements for production of another viral vector C12N2770/18045Special targeting system for viral vectors C12N2770/18051Methods of production or purification of viral material C12N2770/18052relating to complementing cells and packaging systems for producing virus or viral particles C12N2770/18061Methods of inactivation or attenuation C12N2770/18062by genetic engineering C12N2770/18063by chemical treatment C12N2770/18064by serial passage C12N2770/18071Demonstrated in vivo effect C12N2770/18088for redistribution C12N2770/20011Coronaviridae C12N2770/20021Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2770/20022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2770/20023Virus like particles [VLP] C12N2770/20031Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2770/20032Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2770/20033Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory C12N2770/20034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein C12N2770/20041Use of virus, viral particle or viral elements as a vector C12N2770/20042virus or viral particle as vehicle, e.g. encapsulating small organic molecule C12N2770/20043viral genome or elements thereof as genetic vector C12N2770/20044Chimeric viral vector comprising heterologous viral elements for production of another viral vector C12N2770/20045Special targeting system for viral vectors C12N2770/20051Methods of production or purification of viral material C12N2770/20052relating to complementing cells and packaging systems for producing virus or viral particles C12N2770/20061Methods of inactivation or attenuation C12N2770/20062by genetic engineering C12N2770/20063by chemical treatment C12N2770/20064by serial passage C12N2770/20071Demonstrated in vivo effect C12N2770/20088for redistribution C12N2770/22011Dicistroviridae C12N2770/22021Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2770/22022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2770/22023Virus like particles [VLP] C12N2770/22031Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2770/22032Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2770/22033Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory C12N2770/22034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein C12N2770/22041Use of virus, viral particle or viral elements as a vector C12N2770/22042virus or viral particle as vehicle, e.g. encapsulating small organic molecule C12N2770/22043viral genome or elements thereof as genetic vector C12N2770/22044Chimeric viral vector comprising heterologous viral elements for production of another viral vector C12N2770/22045Special targeting system for viral vectors C12N2770/22051Methods of production or purification of viral material C12N2770/22052relating to complementing cells and packaging systems for producing virus or viral particles C12N2770/22061Methods of inactivation or attenuation C12N2770/22062by genetic engineering C12N2770/22063by chemical treatment C12N2770/22064by serial passage C12N2770/22071Demonstrated in vivo effect C12N2770/22088for redistribution C12N2770/24011Flaviviridae C12N2770/24021Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2770/24022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2770/24023Virus like particles [VLP] C12N2770/24031Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2770/24032Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2770/24033Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory C12N2770/24034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein C12N2770/24041Use of virus, viral particle or viral elements as a vector C12N2770/24042virus or viral particle as vehicle, e.g. encapsulating small organic molecule C12N2770/24043viral genome or elements thereof as genetic vector C12N2770/24044Chimeric viral vector comprising heterologous viral elements for production of another viral vector C12N2770/24045Special targeting system for viral vectors C12N2770/24051Methods of production or purification of viral material C12N2770/24052relating to complementing cells and packaging systems for producing virus or viral particles C12N2770/24061Methods of inactivation or attenuation C12N2770/24062by genetic engineering C12N2770/24063by chemical treatment C12N2770/24064by serial passage C12N2770/24071Demonstrated in vivo effect C12N2770/24088for redistribution C12N2770/24111Flavivirus, e.g. yellow fever virus, dengue, JEV C12N2770/24121Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2770/24122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2770/24123Virus like particles [VLP] C12N2770/24131Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2770/24132Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2770/24133Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory C12N2770/24134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein C12N2770/24141Use of virus, viral particle or viral elements as a vector C12N2770/24142virus or viral particle as vehicle, e.g. encapsulating small organic molecule C12N2770/24143viral genome or elements thereof as genetic vector C12N2770/24144Chimeric viral vector comprising heterologous viral elements for production of another viral vector C12N2770/24145Special targeting system for viral vectors C12N2770/24151Methods of production or purification of viral material C12N2770/24152relating to complementing cells and packaging systems for producing virus or viral particles C12N2770/24161Methods of inactivation or attenuation C12N2770/24162by genetic engineering C12N2770/24163by chemical treatment C12N2770/24164by serial passage C12N2770/24171Demonstrated in vivo effect C12N2770/24188for redistribution C12N2770/24211Hepacivirus, e.g. hepatitis C virus, hepatitis G virus C12N2770/24221Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2770/24222New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2770/24223Virus like particles [VLP] C12N2770/24231Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2770/24232Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2770/24233Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory C12N2770/24234Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein C12N2770/24241Use of virus, viral particle or viral elements as a vector C12N2770/24242virus or viral particle as vehicle, e.g. encapsulating small organic molecule C12N2770/24243viral genome or elements thereof as genetic vector C12N2770/24244Chimeric viral vector comprising heterologous viral elements for production of another viral vector C12N2770/24245Special targeting system for viral vectors C12N2770/24251Methods of production or purification of viral material C12N2770/24252relating to complementing cells and packaging systems for producing virus or viral particles C12N2770/24261Methods of inactivation or attenuation C12N2770/24262by genetic engineering C12N2770/24263by chemical treatment C12N2770/24264by serial passage C12N2770/24271Demonstrated in vivo effect C12N2770/24288for redistribution C12N2770/24311Pestivirus, e.g. bovine viral diarrhea virus C12N2770/24321Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2770/24322New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2770/24323Virus like particles [VLP] C12N2770/24331Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2770/24332Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2770/24333Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory C12N2770/24334Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein C12N2770/24341Use of virus, viral particle or viral elements as a vector C12N2770/24342virus or viral particle as vehicle, e.g. encapsulating small organic molecule C12N2770/24343viral genome or elements thereof as genetic vector C12N2770/24344Chimeric viral vector comprising heterologous viral elements for 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C12N2770/28133Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory C12N2770/28134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein C12N2770/28141Use of virus, viral particle or viral elements as a vector C12N2770/28142virus or viral particle as vehicle, e.g. encapsulating small organic molecule C12N2770/28143viral genome or elements thereof as genetic vector C12N2770/28144Chimeric viral vector comprising heterologous viral elements for production of another viral vector C12N2770/28145Special targeting system for viral vectors C12N2770/28151Methods of production or purification of viral material C12N2770/28152relating to complementing cells and packaging systems for producing virus or viral particles C12N2770/28161Methods of inactivation or attenuation C12N2770/28162by genetic engineering C12N2770/28163by chemical treatment C12N2770/28164by serial passage C12N2770/28171Demonstrated in vivo effect C12N2770/28188for redistribution C12N2770/30011Nodaviridae C12N2770/30021Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2770/30022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2770/30023Virus like particles [VLP] C12N2770/30031Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2770/30032Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2770/30033Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory C12N2770/30034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein C12N2770/30041Use of virus, viral particle or viral elements as a vector C12N2770/30042virus or viral particle as vehicle, e.g. encapsulating small organic molecule C12N2770/30043viral genome or elements thereof as genetic vector C12N2770/30044Chimeric viral vector comprising heterologous viral elements for production of another viral vector C12N2770/30045Special targeting system for viral vectors C12N2770/30051Methods of production or purification of viral material C12N2770/30052relating to complementing cells and packaging systems for producing virus or viral particles C12N2770/30061Methods of inactivation or attenuation C12N2770/30062by genetic engineering C12N2770/30063by chemical treatment C12N2770/30064by serial passage C12N2770/30071Demonstrated in vivo effect C12N2770/30088for redistribution C12N2770/32011Picornaviridae C12N2770/32021Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2770/32022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2770/32023Virus like particles [VLP] C12N2770/32031Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2770/32032Use of virus as therapeutic agent, other than 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serial passage C12N2770/32071Demonstrated in vivo effect C12N2770/32088for redistribution C12N2770/32111Aphthovirus, e.g. footandmouth disease virus C12N2770/32121Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2770/32122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2770/32123Virus like particles [VLP] C12N2770/32131Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2770/32132Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2770/32133Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory C12N2770/32134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein C12N2770/32141Use of virus, viral particle or viral elements as a vector C12N2770/32142virus or viral particle as vehicle, e.g. encapsulating small organic molecule C12N2770/32143viral 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genetic engineering C12N2770/32263by chemical treatment C12N2770/32264by serial passage C12N2770/32271Demonstrated in vivo effect C12N2770/32288for redistribution C12N2770/32311Enterovirus C12N2770/32321Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2770/32322New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2770/32323Virus like particles [VLP] C12N2770/32331Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2770/32332Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2770/32333Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory C12N2770/32334Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein C12N2770/32341Use of virus, viral particle or viral elements as a vector C12N2770/32342virus or viral particle as vehicle, e.g. encapsulating small organic molecule C12N2770/32343viral genome or elements thereof as genetic vector C12N2770/32344Chimeric viral vector comprising heterologous viral elements for production of another viral vector C12N2770/32345Special targeting system for viral vectors C12N2770/32351Methods of production or purification of viral material C12N2770/32352relating to complementing cells and packaging systems for producing virus or viral particles C12N2770/32361Methods of inactivation or attenuation C12N2770/32362by genetic engineering C12N2770/32363by chemical treatment C12N2770/32364by serial passage C12N2770/32371Demonstrated in vivo effect C12N2770/32388for redistribution C12N2770/32411Hepatovirus, i.e. hepatitis A virus C12N2770/32421Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2770/32422New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2770/32423Virus like particles [VLP] C12N2770/32431Uses of virus 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inactivation or attenuation C12N2770/32462by genetic engineering C12N2770/32463by chemical treatment C12N2770/32464by serial passage C12N2770/32471Demonstrated in vivo effect C12N2770/32488for redistribution C12N2770/32511Parechovirus, e.g. human parechovirus C12N2770/32521Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2770/32522New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2770/32523Virus like particles [VLP] C12N2770/32531Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2770/32532Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2770/32533Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory C12N2770/32534Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein C12N2770/32541Use of virus, viral particle or viral elements as a vector C12N2770/32542virus or viral particle as vehicle, e.g. encapsulating small organic molecule C12N2770/32543viral genome or elements thereof as genetic vector C12N2770/32544Chimeric viral vector comprising heterologous viral elements for production of another viral vector C12N2770/32545Special targeting system for viral vectors C12N2770/32551Methods of production or purification of viral material C12N2770/32552relating to complementing cells and packaging systems for producing virus or viral particles C12N2770/32561Methods of inactivation or attenuation C12N2770/32562by genetic engineering C12N2770/32563by chemical treatment C12N2770/32564by serial passage C12N2770/32571Demonstrated in vivo effect C12N2770/32588for redistribution C12N2770/32611Poliovirus C12N2770/32621Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2770/32622New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2770/32623Virus like 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particles C12N2770/32661Methods of inactivation or attenuation C12N2770/32662by genetic engineering C12N2770/32663by chemical treatment C12N2770/32664by serial passage C12N2770/32671Demonstrated in vivo effect C12N2770/32688for redistribution C12N2770/32711Rhinovirus C12N2770/32721Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2770/32722New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2770/32723Virus like particles [VLP] C12N2770/32731Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2770/32732Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2770/32733Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory C12N2770/32734Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein C12N2770/32741Use of virus, viral particle or viral elements as a vector C12N2770/32742virus or viral particle as vehicle, e.g. encapsulating small organic molecule C12N2770/32743viral genome or elements thereof as genetic vector C12N2770/32744Chimeric viral vector comprising heterologous viral elements for production of another viral vector C12N2770/32745Special targeting system for viral vectors C12N2770/32751Methods of production or purification of viral material C12N2770/32752relating to complementing cells and packaging systems for producing virus or viral particles C12N2770/32761Methods of inactivation or attenuation C12N2770/32762by genetic engineering C12N2770/32763by chemical treatment C12N2770/32764by serial passage C12N2770/32771Demonstrated in vivo effect C12N2770/32788for redistribution C12N2770/34011Potyviridae C12N2770/34021Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2770/34022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2770/34023Virus 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viral particles C12N2770/34061Methods of inactivation or attenuation C12N2770/34062by genetic engineering C12N2770/34063by chemical treatment C12N2770/34064by serial passage C12N2770/34071Demonstrated in vivo effect C12N2770/34088for redistribution C12N2770/36011Togaviridae C12N2770/36021Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2770/36022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2770/36023Virus like particles [VLP] C12N2770/36031Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2770/36032Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2770/36033Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory C12N2770/36034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein C12N2770/36041Use of virus, viral particle or viral elements as a vector C12N2770/36042virus or viral particle as vehicle, e.g. encapsulating small organic molecule C12N2770/36043viral genome or elements thereof as genetic vector C12N2770/36044Chimeric viral vector comprising heterologous viral elements for production of another viral vector C12N2770/36045Special targeting system for viral vectors C12N2770/36051Methods of production or purification of viral material C12N2770/36052relating to complementing cells and packaging systems for producing virus or viral particles C12N2770/36061Methods of inactivation or attenuation C12N2770/36062by genetic engineering C12N2770/36063by chemical treatment C12N2770/36064by serial passage C12N2770/36071Demonstrated in vivo effect C12N2770/36088for redistribution C12N2770/36111Alphavirus, e.g. Sindbis virus, VEE, EEE, WEE, Semliki C12N2770/36121Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2770/36122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2770/36123Virus like particles [VLP] C12N2770/36131Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2770/36132Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2770/36133Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory C12N2770/36134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein C12N2770/36141Use of virus, viral particle or viral elements as a vector C12N2770/36142virus or viral particle as vehicle, e.g. encapsulating small organic molecule C12N2770/36143viral genome or elements thereof as genetic vector C12N2770/36144Chimeric viral vector comprising heterologous viral elements for production of another viral vector C12N2770/36145Special targeting system for viral vectors C12N2770/36151Methods of production or purification of viral material C12N2770/36152relating to complementing cells and packaging systems for producing virus or viral particles C12N2770/36161Methods of inactivation or attenuation C12N2770/36162by genetic engineering C12N2770/36163by chemical treatment C12N2770/36164by serial passage C12N2770/36171Demonstrated in vivo effect C12N2770/36188for redistribution C12N2770/36211Rubivirus, e.g. rubella virus C12N2770/36221Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2770/36222New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2770/36223Virus like particles [VLP] C12N2770/36231Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2770/36232Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2770/36233Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory C12N2770/36234Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral 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elements as a vector C12N2795/16042virus or viral particle as vehicle, e.g. encapsulating small organic molecule C12N2795/16043viral genome or elements thereof as genetic vector C12N2795/16044Chimeric viral vector comprising heterologous viral elements for production of another viral vector C12N2795/16045Special targeting system for viral vectors C12N2795/16051Methods of production or purification of viral material C12N2795/16052relating to complementing cells and packaging systems for producing virus or viral particles C12N2795/16061Methods of inactivation or attenuation C12N2795/16062by genetic engineering C12N2795/16063by chemical treatment C12N2795/16064by serial passage C12N2795/16071Demonstrated in vivo effect C12N2795/16088for redistribution C12N2795/18011ssRNA Bacteriophages positive-sense C12N2795/18021Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2795/18022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2795/18023Virus like particles [VLP] C12N2795/18031Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2795/18032Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2795/18033Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory C12N2795/18034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein C12N2795/18041Use of virus, viral particle or viral elements as a vector C12N2795/18042virus or viral particle as vehicle, e.g. encapsulating small organic molecule C12N2795/18043viral genome or elements thereof as genetic vector C12N2795/18044Chimeric viral vector comprising heterologous viral elements for production of another viral vector C12N2795/18045Special targeting system for viral vectors C12N2795/18051Methods of production or purification of viral material C12N2795/18052relating to complementing cells and packaging systems for producing virus or viral particles C12N2795/18061Methods of inactivation or attenuation C12N2795/18062by genetic engineering C12N2795/18063by chemical treatment C12N2795/18064by serial passage C12N2795/18071Demonstrated in vivo effect C12N2795/18088for redistribution C12N2795/18111Leviviridae C12N2795/18121Viruses as such, e.g. new isolates, mutants or their genomic sequences C12N2795/18122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes C12N2795/18123Virus like particles [VLP] C12N2795/18131Uses of virus other than therapeutic or vaccine, e.g. disinfectant C12N2795/18132Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent C12N2795/18133Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory C12N2795/18134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein C12N2795/18141Use of virus, viral particle or viral elements as a vector C12N2795/18142virus or viral particle as vehicle, e.g. encapsulating small organic molecule C12N2795/18143viral genome or elements thereof as genetic vector C12N2795/18144Chimeric viral vector comprising heterologous viral elements for production of another viral vector C12N2795/18145Special targeting system for viral vectors C12N2795/18151Methods of production or purification of viral material C12N2795/18152relating to complementing cells and packaging systems for producing virus or viral particles C12N2795/18161Methods of inactivation or attenuation C12N2795/18162by genetic engineering C12N2795/18163by chemical treatment C12N2795/18164by serial passage C12N2795/18171Demonstrated in vivo effect C12N2795/18188for redistribution C12N2796/00Viruses not covered by groups C12N2710/00 - C12N2795/00 C12N2799/00Uses of viruses From 2012-03-15 codes in the range C12N2799/00 - C12N2799/06 are no longer used for the classification of new documents. The documents in this range are being reclassified to the corresponding codes in C12N2710/00-C12N2795/00 C12N2799/02as vector C12N2799/021for the expression of a heterologous nucleic acid C12N2799/022where the vector is derived from an adenovirus C12N2799/023where the vector is derived from a poxvirus C12N2799/025where the vector is derived from a parvovirus C12N2799/026where the vector is derived from a baculovirus C12N2799/027where the vector is derived from a retrovirus C12N2799/028where the vector is derived from a herpesvirus C12N2799/04in vivo C12N2799/06in vitro C12N2800/00Nucleic acids vectors C12N2800/10Plasmid DNA C12N2800/101for bacteria C12N2800/102for yeast C12N2800/103for invertebrates C12N2800/105for insects C12N2800/106for vertebrates C12N2800/107for mammalian C12N2800/108episomal vectors C12N2800/20Pseudochromosomes, minichrosomosomes C12N2800/202of bacteriophage origin C12N2800/204of bacterial origin, e.g. BAC C12N2800/206of yeast origin, e.g. YAC, 2u C12N2800/208of mammalian origin, e.g. minichromosome C12N2800/22Vectors comprising a coding region that has been codon optimised for expression in a respective host C12N2800/24Vectors characterised by the absence of particular element, e.g. selectable marker, viral origin of replication C12N2800/30Vector systems comprising sequences for excision in presence of a recombinase, e.g. loxP or FRT C12N2800/40Systems of functionally co-operating vectors C12N2800/50Vectors for producing vectors C12N2800/60Vectors containing traps for, e.g. exons, promoters C12N2800/70Vectors containing special elements for cloning, e.g. topoisomerase, adaptor sites C12N2800/80Vectors containing sites for inducing double-stranded breaks, e.g. meganuclease restriction sites C12N2800/90Vectors containing a transposable element C12N2800/95Protection of vectors from inactivation by agents such as antibodies or enzymes, e.g. using polymers C12N2810/00Vectors comprising a targeting moiety C12N2810/10Vectors comprising a non-peptidic targeting moiety C12N2810/40Vectors comprising a peptide as targeting moiety, e.g. a synthetic peptide, from undefined source C12N2810/405Vectors comprising RGD peptide C12N2810/50Vectors comprising as targeting moiety peptide derived from defined protein C12N2810/55from bacteria C12N2810/60from viruses C12N2810/6009dsDNA viruses C12N2810/6018Adenoviridae C12N2810/6027ssDNA viruses C12N2810/6036DNA rev transcr viruses C12N2810/6045RNA rev transcr viruses C12N2810/6054Retroviridae C12N2810/6063ds RNA viruses C12N2810/6072negative strand RNA viruses C12N2810/6081rhabdoviridae, e.g. VSV C12N2810/609positive strand RNA viruses C12N2810/65from plants C12N2810/70from fungi C12N2810/75from invertebrates C12N2810/80from vertebrates C12N2810/85mammalian C12N2810/851from growth factorsfrom growth regulators C12N2810/852from cytokinesfrom lymphokinesfrom interferons C12N2810/853from tumor necrosis factor, TNF C12N2810/854from hormones C12N2810/855from receptorsfrom cell surface antigensfrom cell surface determinants C12N2810/856from integrins C12N2810/857from blood coagulation or fibrinolysis factors C12N2810/858from apolipopeptides C12N2810/859from immunoglobulins C12N2810/90avian C12N2820/00Vectors comprising a special origin of replication system C12N2820/002inducible or controllable C12N2820/005cell-cycle regulated C12N2820/007tissue or cell-specific C12N2820/10multiple origins of replication C12N2820/55from bacteria C12N2820/60from viruses C12N2820/65from plants C12N2820/70from fungi C12N2820/702yeast C12N2820/704S. cerevisae C12N2820/706S. pombe C12N2820/708C. albicans C12N2820/75from invertebrates C12N2820/80from vertebrates C12N2820/85mammalian C12N2820/90avian C12N2830/00Vector systems having a special element relevant for transcription C12N2830/001controllable enhancer/promoter combination C12N2830/002inducible enhancer/promoter combination, e.g. hypoxia, iron, transcription factor C12N2830/003tet inducible C12N2830/005repressible enhancer/promoter combination, e.g. KRAB C12N2830/006tet repressible C12N2830/007cell cycle specific enhancer/promoter combination C12N2830/008cell type or tissue specific enhancer/promoter combination C12N2830/15chimeric enhancer/promoter combination C12N2830/20transcription of more than one cistron C12N2830/205bidirectional C12N2830/30being an enhancer not forming part of the promoter region C12N2830/32being an silencer not forming part of the promoter region C12N2830/34being a transcription initiation element C12N2830/36being a transcription termination element C12N2830/38being a stuffer C12N2830/40being an insulator C12N2830/42being an intron or intervening sequence for splicing and/or stability of RNA C12N2830/46elements influencing chromatin structure, e.g. scaffold/matrix attachment region, methylation free island C12N2830/48regulating transport or export of RNA, e.g. RRE, PRE, WPRE, CTE C12N2830/50regulating RNA stability, not being an intron, e.g. poly A signal C12N2830/52encoding ribozyme for self-inactivation C12N2830/55from bacteria C12N2830/60from viruses C12N2830/65from plants C12N2830/70from fungi C12N2830/702yeast C12N2830/704S. cerevisiae C12N2830/706S. pombe C12N2830/708C. albicans C12N2830/75from invertebrates C12N2830/80from vertebrates C12N2830/85mammalian C12N2830/90avian C12N2840/00Vectors comprising a special translation-regulating system C12N2840/002controllable or inducible C12N2840/005cell cycle specific C12N2840/007cell or tissue specific C12N2840/10regulates levels of translation C12N2840/102inhibiting translation C12N2840/105enhancing translation C12N2840/107inhibiting translational read-through C12N2840/20translation of more than one cistron C12N2840/203having an IRES C12N2840/206having multiple IRES C12N2840/44being a specific part of the splice mechanism, e.g. donor, acceptor C12N2840/445for trans-splicing, e.g. polypyrimidine tract, branch point splicing C12N2840/50utilisation of non-ATG initiation codonThis groups covers artificial modification only, i.e. naturally occurring use of non-ATG start codon is not classified here C12N2840/55from bacteria C12N2840/60from viruses C12N2840/65from plants C12N2840/70from fungi C12N2840/702yeast C12N2840/704S. cerevisiae C12N2840/706S. pombe C12N2840/708C. albicans C12N2840/75from invertebrates C12N2840/80from vertebrates C12N2840/85mammalian C12N2840/90avian C12N2999/00Further aspects of viruses or vectors not covered by groups C12N2710/00 - C12N2796/00 or C12N2800/00This group is for classification of patent and non-patent literature documents.When classifying non-patent literature in this group, classification must also be given for the relevant CPC groups, to define the technical area to which they relate. C12N2999/002Adverse teaching C12N2999/005Biological teaching, e.g. a link between protein and disease, new virus causing pandemic C12N2999/007Technological advancements, e.g. new system for producing known virus, cre-lox system for production of transgenic animals